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Design, Synthesis, and Evaluation of New Hybrid Derivatives of 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one as Potential Dual Inhibitors of Blood Coagulation Factors Xa and XIa.

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Title: Design, Synthesis, and Evaluation of New Hybrid Derivatives of 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one as Potential Dual Inhibitors of Blood Coagulation Factors Xa and XIa.
Authors: Skoptsova AA; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia., Geronikaki A; School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece., Novichikhina NP; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia., Sulimov AV; Research Computing Center, Lomonosov Moscow State University, 119992 Moscow, Russia., Ilin IS; Research Computing Center, Lomonosov Moscow State University, 119992 Moscow, Russia., Sulimov VB; Research Computing Center, Lomonosov Moscow State University, 119992 Moscow, Russia., Bykov GA; Department of Biophysics at the Faculty of Physics, Lomonosov Moscow State University, 119992 Moscow, Russia., Podoplelova NA; Center for Theoretical Problems of Physicochemical Pharmakology, 119991 Moscow, Russia., Pyankov OV; State Research Center of Virology and Biotechnology 'Vector', 630559 Koltsovo, Russia., Shikhaliev KS; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia.
Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 11; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 11.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Design, Synthesis, and Evaluation of New Hybrid Derivatives of 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one as Potential Dual Inhibitors of Blood Coagulation Factors Xa and XIa.
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  Data: <searchLink fieldCode="AU" term="%22Skoptsova+AA%22">Skoptsova AA</searchLink>; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia.<br /><searchLink fieldCode="AU" term="%22Geronikaki+A%22">Geronikaki A</searchLink>; School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Novichikhina+NP%22">Novichikhina NP</searchLink>; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia.<br /><searchLink fieldCode="AU" term="%22Sulimov+AV%22">Sulimov AV</searchLink>; Research Computing Center, Lomonosov Moscow State University, 119992 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Ilin+IS%22">Ilin IS</searchLink>; Research Computing Center, Lomonosov Moscow State University, 119992 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Sulimov+VB%22">Sulimov VB</searchLink>; Research Computing Center, Lomonosov Moscow State University, 119992 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Bykov+GA%22">Bykov GA</searchLink>; Department of Biophysics at the Faculty of Physics, Lomonosov Moscow State University, 119992 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Podoplelova+NA%22">Podoplelova NA</searchLink>; Center for Theoretical Problems of Physicochemical Pharmakology, 119991 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Pyankov+OV%22">Pyankov OV</searchLink>; State Research Center of Virology and Biotechnology 'Vector', 630559 Koltsovo, Russia.<br /><searchLink fieldCode="AU" term="%22Shikhaliev+KS%22">Shikhaliev KS</searchLink>; Department of Organic Chemistry, Faculty of Chemistry, Voronezh State University, 1 Universitetskaya Sq., 394018 Voronezh, Russia.
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              Text: 2024 Jan 11
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