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Interleukin 21 Drives a Hypermetabolic State and CD4+ T-Cell-Associated Pathogenicity in Chronic Intestinal Inflammation.

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Title: Interleukin 21 Drives a Hypermetabolic State and CD4+ T-Cell-Associated Pathogenicity in Chronic Intestinal Inflammation.
Authors: Bamidele AO; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota; Department of Immunology, Mayo Clinic, Rochester, Minnesota. Electronic address: Bamidele.Adebowale@mayo.edu., Mishra SK; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Piovezani Ramos G; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Hirsova P; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Klatt EE; Department of Immunology, Mayo Clinic, Rochester, Minnesota., Abdelrahman LM; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Sagstetter MR; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Davidson HM; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Fehrenbach PJ; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Valenzuela-Pérez L; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Kim Lee HS; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Zhang S; Mayo Clinic Metabolomics Core, Mayo Clinic, Rochester, Minnesota; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota., Aguirre Lopez A; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Kurdi AT; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Westphal MS; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Gonzalez MM; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Gaballa JM; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Kosinsky RL; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota., Lee HE; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Smyrk TC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Bantug G; Immunobiology Laboratory, Department of Biomedicine, University Hospital of Basel, Basel, Switzerland., Gades NM; Department of Comparative Medicine, Mayo Clinic, Scottsdale, Arizona., Faubion WA Jr; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Source: Gastroenterology [Gastroenterology] 2024 May; Vol. 166 (5), pp. 826-841.e19. Date of Electronic Publication: 2024 Jan 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Interleukin 21 Drives a Hypermetabolic State and CD4<superscript>+</superscript> T-Cell-Associated Pathogenicity in Chronic Intestinal Inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Bamidele+AO%22">Bamidele AO</searchLink>; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota; Department of Immunology, Mayo Clinic, Rochester, Minnesota. Electronic address: Bamidele.Adebowale@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Mishra+SK%22">Mishra SK</searchLink>; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Piovezani+Ramos+G%22">Piovezani Ramos G</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Hirsova+P%22">Hirsova P</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Klatt+EE%22">Klatt EE</searchLink>; Department of Immunology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Abdelrahman+LM%22">Abdelrahman LM</searchLink>; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Sagstetter+MR%22">Sagstetter MR</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Davidson+HM%22">Davidson HM</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Fehrenbach+PJ%22">Fehrenbach PJ</searchLink>; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Valenzuela-Pérez+L%22">Valenzuela-Pérez L</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Kim+Lee+HS%22">Kim Lee HS</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Mayo Clinic Metabolomics Core, Mayo Clinic, Rochester, Minnesota; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Aguirre+Lopez+A%22">Aguirre Lopez A</searchLink>; Immunometabolism and Mucosal Immunity Laboratory, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Kurdi+AT%22">Kurdi AT</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Westphal+MS%22">Westphal MS</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Gonzalez+MM%22">Gonzalez MM</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Gaballa+JM%22">Gaballa JM</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Kosinsky+RL%22">Kosinsky RL</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Lee+HE%22">Lee HE</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Smyrk+TC%22">Smyrk TC</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Bantug+G%22">Bantug G</searchLink>; Immunobiology Laboratory, Department of Biomedicine, University Hospital of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gades+NM%22">Gades NM</searchLink>; Department of Comparative Medicine, Mayo Clinic, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Faubion+WA+Jr%22">Faubion WA Jr</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
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  Data: <searchLink fieldCode="JN" term="%220374630%22">Gastroenterology</searchLink> [Gastroenterology] 2024 May; Vol. 166 (5), pp. 826-841.e19. <i>Date of Electronic Publication: </i>2024 Jan 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0374630 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0012 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200165085%22">00165085 </searchLink><i>NLM ISO Abbreviation: </i>Gastroenterology <i>Subsets: </i>MEDLINE
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