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PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease.

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Title: PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease.
Authors: Kocheise L; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Piseddu I; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine II, University Hospital, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany., Vonderlin J; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatology and Gastroenterology, Charité-Universitätsmedizin Berlin, Berlin, Germany., Tjwa ET; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Gastroenterology and Hepatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Buescher G; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Meunier L; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Service Hépato-Gastro Entérologie, Hôpital St-Eloi, CHU Montpellier, Montpellier, France., Goeggelmann P; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany., Fianchi F; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; CEMAD-Centro Malattie dell'Apparato Digerente, Fondazione Policlinico Universitario Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy., Dumortier J; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Service d'hépato-gastroentérologie, Hôpital Edouard Herriot - Hospices civils de Lyon, Université de Lyon, Lyon, France., Riveiro Barciela M; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Liver Unit, Department of Internal Medicine, Hospital Universitari Valle d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain., Gevers TJG; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Gastroenterology and Hepatology, Maastricht University Medical Centre, Maastricht, Netherlands.; Nutrim School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, Netherlands., Terziroli Beretta-Piccoli B; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Epatocentro Ticino, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, United Kingdom., Londoño MC; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Liver Unit, Hospital Clinic Barcelona, FCRB-IDIBAPS, CIBEREHD, University of Barcelona, Barcelona, Spain., Frankova S; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czechia., Roesner T; Department of Medical Oncology, National Center of Tumor Diseases (NCT) Heidelberg and Universitätsklinikum Heidelberg, Heidelberg, Germany., Joerg V; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Schmidt C; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Glaser F; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Sutter JP; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Fründt TW; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Lohse AW; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Huber S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., von Felden J; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Sebode M; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany., Schulze K; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.
Source: Frontiers in immunology [Front Immunol] 2024 Jan 10; Vol. 14, pp. 1326078. Date of Electronic Publication: 2024 Jan 10 (Print Publication: 2023).
Publication Type: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease.
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  Data: <searchLink fieldCode="AU" term="%22Kocheise+L%22">Kocheise L</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Piseddu+I%22">Piseddu I</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Medicine II, University Hospital, Ludwig-Maximilians-Universität (LMU) München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Vonderlin+J%22">Vonderlin J</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatology and Gastroenterology, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Tjwa+ET%22">Tjwa ET</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Gastroenterology and Hepatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Buescher+G%22">Buescher G</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Meunier+L%22">Meunier L</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Service Hépato-Gastro Entérologie, Hôpital St-Eloi, CHU Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Goeggelmann+P%22">Goeggelmann P</searchLink>; Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fianchi+F%22">Fianchi F</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; CEMAD-Centro Malattie dell'Apparato Digerente, Fondazione Policlinico Universitario Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Dumortier+J%22">Dumortier J</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Service d'hépato-gastroentérologie, Hôpital Edouard Herriot - Hospices civils de Lyon, Université de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Riveiro+Barciela+M%22">Riveiro Barciela M</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Liver Unit, Department of Internal Medicine, Hospital Universitari Valle d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gevers+TJG%22">Gevers TJG</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Gastroenterology and Hepatology, Maastricht University Medical Centre, Maastricht, Netherlands.; Nutrim School for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Terziroli+Beretta-Piccoli+B%22">Terziroli Beretta-Piccoli B</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Epatocentro Ticino, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland.; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Londoño+MC%22">Londoño MC</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Liver Unit, Hospital Clinic Barcelona, FCRB-IDIBAPS, CIBEREHD, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Frankova+S%22">Frankova S</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.; Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czechia.<br /><searchLink fieldCode="AU" term="%22Roesner+T%22">Roesner T</searchLink>; Department of Medical Oncology, National Center of Tumor Diseases (NCT) Heidelberg and Universitätsklinikum Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Joerg+V%22">Joerg V</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+C%22">Schmidt C</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Glaser+F%22">Glaser F</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sutter+JP%22">Sutter JP</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fründt+TW%22">Fründt TW</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lohse+AW%22">Lohse AW</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Huber+S%22">Huber S</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Felden+J%22">von Felden J</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sebode+M%22">Sebode M</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schulze+K%22">Schulze K</searchLink>; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hamburg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2024 Jan 10; Vol. 14, pp. 1326078. <i>Date of Electronic Publication: </i>2024 Jan 10 (<i>Print Publication: </i>2023).
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