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A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations.

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Title: A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations.
Authors: Anderson MAE; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Gonzalez E; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; Animal and Plant Health Agency, Woodham Lane, Addlestone, Surrey, KT15 3NB, UK., Edgington MP; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Ang JXD; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Purusothaman DK; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; MRC-University of Glasgow Centre for Virus Research, Henry Wellcome Building, 464 Bearsden Road, Glasgow, G61 1QH, UK., Shackleford L; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Nevard K; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK., Verkuijl SAN; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; Department of Biology, University of Oxford, 11a Mansfield Road, Oxford, OX1 3SZ, UK., Harvey-Samuel T; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK., Leftwich PT; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK.; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, Norfolk, NR4 7TJ, UK., Esvelt K; Media Laboratory, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Alphey L; Arthropod Genetics, The Pirbright Institute, Ash Road, Pirbright, GU24 0HN, UK. luke.alphey@york.ac.uk.; The Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK. luke.alphey@york.ac.uk.
Source: Nature communications [Nat Commun] 2024 Jan 25; Vol. 15 (1), pp. 729. Date of Electronic Publication: 2024 Jan 25.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations.
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