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ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.

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Title: ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.
Authors: Chan TS; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.; Division of Gastroenterology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taiwan.; School of Medicine, College of Medicine, Taipei Medical University, Taiwan.; Pancreatic Cancer Group, Taipei Cancer Center, Taipei Medical University, Taiwan., Cheng LH; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.; Core Laboratory of Organoids Technology, Office of R&D, Taipei Medical University, Taiwan., Hsu CC; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan., Yang PM; Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taiwan., Liao TY; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan., Hsieh HY; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan., Lin PC; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan., HuangFu WC; Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taiwan., Chuu CP; Institute of Cellular and System Medicine, National Health Research Institutes, Miaoli, Taiwan., Tsai KK; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.; Division of Gastroenterology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taiwan.; Pancreatic Cancer Group, Taipei Cancer Center, Taipei Medical University, Taiwan.; Core Laboratory of Organoids Technology, Office of R&D, Taipei Medical University, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taiwan.
Source: Molecular oncology [Mol Oncol] 2024 Mar; Vol. 18 (3), pp. 562-579. Date of Electronic Publication: 2024 Jan 26.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
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  Data: ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.
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  Data: <searchLink fieldCode="AU" term="%22Chan+TS%22">Chan TS</searchLink>; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.; Division of Gastroenterology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taiwan.; School of Medicine, College of Medicine, Taipei Medical University, Taiwan.; Pancreatic Cancer Group, Taipei Cancer Center, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+LH%22">Cheng LH</searchLink>; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.; Core Laboratory of Organoids Technology, Office of R&D, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CC%22">Hsu CC</searchLink>; School of Medicine, College of Medicine, I-Shou University, Kaohsiung City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+PM%22">Yang PM</searchLink>; Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+TY%22">Liao TY</searchLink>; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+HY%22">Hsieh HY</searchLink>; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PC%22">Lin PC</searchLink>; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22HuangFu+WC%22">HuangFu WC</searchLink>; Master Program in Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chuu+CP%22">Chuu CP</searchLink>; Institute of Cellular and System Medicine, National Health Research Institutes, Miaoli, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+KK%22">Tsai KK</searchLink>; Laboratory of Advanced Molecular Therapeutics, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taiwan.; Division of Gastroenterology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taiwan.; Pancreatic Cancer Group, Taipei Cancer Center, Taipei Medical University, Taiwan.; Core Laboratory of Organoids Technology, Office of R&D, Taipei Medical University, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2024 Mar; Vol. 18 (3), pp. 562-579. <i>Date of Electronic Publication: </i>2024 Jan 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Inc%22">John Wiley & Sons, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101308230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-0261 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215747891%22">15747891 </searchLink><i>NLM ISO Abbreviation: </i>Mol Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1002/1878-0261.13589
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      – TitleFull: ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells.
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              Text: 2024 Mar
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