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Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.

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Title: Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.
Authors: Wolpe AG; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Luse MA; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA., Baryiames C; Department of Chemistry, University of Virginia, Charlottesville, VA 22904, USA., Schug WJ; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA., Wolpe JB; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Johnstone SR; Fralin Biomedical Research Institute at Virginia Tech Carilion School of Medicine, Center for Vascular and Heart Research, Roanoke, VA 24016, USA.; Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24060, USA., Dunaway LS; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Juśkiewicz ZJ; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Loeb SA; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA., Askew Page HR; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Chen YL; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Sabapathy V; Center for Immunity, Inflammation, and Regenerative Medicine (CIIR), University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Pavelec CM; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Wakefield B; Department of Anatomy and Cell Biology, University of Western Ontario, London, ON N6A 5C1, Canada., Cifuentes-Pagano E; Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA., Artamonov MV; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Somlyo AV; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Straub AC; Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15213, USA., Sharma R; Center for Immunity, Inflammation, and Regenerative Medicine (CIIR), University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Beier F; Department of Physiology and Pharmacology, University of Western Ontario, London, ON N6A 5C1, Canada., Barrett EJ; Department of Medicine, Division of Endocrinology and Metabolism, University of Virginia School of Medicine, Charlottesville, VA 22903, USA., Leitinger N; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA., Pagano PJ; Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA., Sonkusare SK; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA., Redemann S; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.; Center for Membrane and Cell Physiology, University of Virginia School of Medicine, Charlottesville, VA 22903, USA., Columbus L; Department of Chemistry, University of Virginia, Charlottesville, VA 22904, USA., Penuela S; Department of Anatomy and Cell Biology, University of Western Ontario, London, ON N6A 5C1, Canada.; Department of Oncology (Division of Experimental Oncology), Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON N6A 5W9, Canada., Isakson BE; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
Source: Science signaling [Sci Signal] 2024 Jan 30; Vol. 17 (821), pp. eadg2622. Date of Electronic Publication: 2024 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
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  Data: Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.
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Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.; Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.
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