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Expanding the ligandable proteome by paralog hopping with covalent probes.

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Title: Expanding the ligandable proteome by paralog hopping with covalent probes.
Authors: Zhang Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Liu Z; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Hirschi M; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Brodsky O; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Johnson E; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Won SJ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Nagata A; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Petroski MD; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Majmudar JD; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Cambridge, MA 02139, USA., Niessen S; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.; Current address: Belharra Therapeutics, 3985 Sorrento Valley Blvd suite c, San Diego, CA 92121., VanArsdale T; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Gilbert AM; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Groton, CT 06340, USA., Hayward MM; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Groton, CT 06340, USA.; Current address: Magnet Biomedicine, 321 Harrison Ave., Suite 600, Boston, MA 02118, USA., Stewart AE; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Nager AR; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Melillo B; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Cravatt B; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 19. Date of Electronic Publication: 2024 Jan 19.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Expanding the ligandable proteome by paralog hopping with covalent probes.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA.<br /><searchLink fieldCode="AU" term="%22Hirschi+M%22">Hirschi M</searchLink>; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Brodsky+O%22">Brodsky O</searchLink>; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+E%22">Johnson E</searchLink>; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Won+SJ%22">Won SJ</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA.<br /><searchLink fieldCode="AU" term="%22Nagata+A%22">Nagata A</searchLink>; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Petroski+MD%22">Petroski MD</searchLink>; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Majmudar+JD%22">Majmudar JD</searchLink>; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Niessen+S%22">Niessen S</searchLink>; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.; Current address: Belharra Therapeutics, 3985 Sorrento Valley Blvd suite c, San Diego, CA 92121.<br /><searchLink fieldCode="AU" term="%22VanArsdale+T%22">VanArsdale T</searchLink>; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Gilbert+AM%22">Gilbert AM</searchLink>; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Groton, CT 06340, USA.<br /><searchLink fieldCode="AU" term="%22Hayward+MM%22">Hayward MM</searchLink>; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Groton, CT 06340, USA.; Current address: Magnet Biomedicine, 321 Harrison Ave., Suite 600, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Stewart+AE%22">Stewart AE</searchLink>; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Nager+AR%22">Nager AR</searchLink>; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.<br /><searchLink fieldCode="AU" term="%22Melillo+B%22">Melillo B</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA.<br /><searchLink fieldCode="AU" term="%22Cravatt+B%22">Cravatt B</searchLink>; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA.
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              Text: 2024 Jan 19
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