Expanding the ligandable proteome by paralog hopping with covalent probes.
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| Title: | Expanding the ligandable proteome by paralog hopping with covalent probes. |
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| Authors: | Zhang Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Liu Z; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Hirschi M; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Brodsky O; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Johnson E; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Won SJ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Nagata A; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Petroski MD; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Majmudar JD; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Cambridge, MA 02139, USA., Niessen S; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA.; Current address: Belharra Therapeutics, 3985 Sorrento Valley Blvd suite c, San Diego, CA 92121., VanArsdale T; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Gilbert AM; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Groton, CT 06340, USA., Hayward MM; Discovery Sciences, Pfizer Research and Development, Pfizer Inc., Groton, CT 06340, USA.; Current address: Magnet Biomedicine, 321 Harrison Ave., Suite 600, Boston, MA 02118, USA., Stewart AE; Medicine Design, Pfizer Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Nager AR; Oncology Research and Development, Pfizer Inc., La Jolla, CA 92121, USA., Melillo B; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA., Cravatt B; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037 USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 19. Date of Electronic Publication: 2024 Jan 19. |
| Publication Type: | Preprint; Journal Article |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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