Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II-III colorectal cancer from the SCOT and QUASAR 2 trials: a retrospective analysis.

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Title: Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II-III colorectal cancer from the SCOT and QUASAR 2 trials: a retrospective analysis.
Authors: Frei AL; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Life Science Zurich Graduate School, PhD Program in Biomedicine, University of Zurich, Zurich, Switzerland., McGuigan A; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sinha RRAK; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Jabbar F; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gneo L; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tomasevic T; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Harkin A; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Iveson T; Southampton University, Southampton, UK., Saunders MP; The Christie NHS Foundation Trust, Manchester, UK., Oien KA; School of Cancer Sciences, University of Glasgow, Glasgow, UK; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Maka N; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Pezzella F; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK., Campo L; Department of Oncology, University of Oxford, Oxford, UK., Browne M; Department of Oncology, University of Oxford, Oxford, UK., Glaire M; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kildal W; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway., Danielsen HE; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway., Hay J; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Sansom O; School of Cancer Sciences, University of Glasgow, Glasgow, UK; Cancer Research UK Beatson Institute of Cancer Research, Glasgow, UK; Cancer Research UK Scotland Centre, Glasgow and Edinburgh, UK., Kelly C; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK., Tomlinson I; Department of Oncology, University of Oxford, Oxford, UK., Kerr R; Department of Oncology, University of Oxford, Oxford, UK., Kerr D; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK., Domingo E; Department of Oncology, University of Oxford, Oxford, UK; Cancer Research UK Scotland Centre, Glasgow and Edinburgh, UK., Church DN; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: david.church@well.ox.ac.uk., Koelzer VH; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Nuffield Department of Medicine, University of Oxford, Oxford, UK; Department of Oncology, University of Oxford, Oxford, UK.
Corporate Authors: TransSCOT consortium
Source: The Lancet. Oncology [Lancet Oncol] 2024 Feb; Vol. 25 (2), pp. 198-211.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
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  Data: Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II-III colorectal cancer from the SCOT and QUASAR 2 trials: a retrospective analysis.
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  Data: <searchLink fieldCode="AU" term="%22Frei+AL%22">Frei AL</searchLink>; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Life Science Zurich Graduate School, PhD Program in Biomedicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22McGuigan+A%22">McGuigan A</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Sinha+RRAK%22">Sinha RRAK</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jabbar+F%22">Jabbar F</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Gneo+L%22">Gneo L</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Tomasevic+T%22">Tomasevic T</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Harkin+A%22">Harkin A</searchLink>; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Iveson+T%22">Iveson T</searchLink>; Southampton University, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Saunders+MP%22">Saunders MP</searchLink>; The Christie NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Oien+KA%22">Oien KA</searchLink>; School of Cancer Sciences, University of Glasgow, Glasgow, UK; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Maka+N%22">Maka N</searchLink>; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Pezzella+F%22">Pezzella F</searchLink>; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Campo+L%22">Campo L</searchLink>; Department of Oncology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Browne+M%22">Browne M</searchLink>; Department of Oncology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Glaire+M%22">Glaire M</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kildal+W%22">Kildal W</searchLink>; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Danielsen+HE%22">Danielsen HE</searchLink>; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Hay+J%22">Hay J</searchLink>; Glasgow Tissue Research Facility, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Edwards+J%22">Edwards J</searchLink>; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Sansom+O%22">Sansom O</searchLink>; School of Cancer Sciences, University of Glasgow, Glasgow, UK; Cancer Research UK Beatson Institute of Cancer Research, Glasgow, UK; Cancer Research UK Scotland Centre, Glasgow and Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Kelly+C%22">Kelly C</searchLink>; Cancer Research UK Glasgow Clinical Trials Unit, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Tomlinson+I%22">Tomlinson I</searchLink>; Department of Oncology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kerr+R%22">Kerr R</searchLink>; Department of Oncology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kerr+D%22">Kerr D</searchLink>; Nuffield Division of Clinical and Laboratory Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Domingo+E%22">Domingo E</searchLink>; Department of Oncology, University of Oxford, Oxford, UK; Cancer Research UK Scotland Centre, Glasgow and Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Church+DN%22">Church DN</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: david.church@well.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Koelzer+VH%22">Koelzer VH</searchLink>; Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Nuffield Department of Medicine, University of Oxford, Oxford, UK; Department of Oncology, University of Oxford, Oxford, UK.
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