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Discovery of a novel series of selective macrocyclic PKCTheta inhibitors.

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Bibliographic Details
Title: Discovery of a novel series of selective macrocyclic PKCTheta inhibitors.
Authors: Crosignani S; Galderma SA, Av. d'Ouchy 4, 1006 Lausanne, Switzerland. Electronic address: stefano.crosignani@gmail.com., Campos S; Pharmaron Discovery & Early Development, West Hill Innovation Park, Hertford Road, Hoddesdon, Hertfordshire EN11 9FH, UK., Bouix-Peter C; Galderma SA, Av. d'Ouchy 4, 1006 Lausanne, Switzerland., Harris C; Galderma SA, Av. d'Ouchy 4, 1006 Lausanne, Switzerland., Talbot E; Pharmaron Discovery & Early Development, West Hill Innovation Park, Hertford Road, Hoddesdon, Hertfordshire EN11 9FH, UK., Hu H; Pharmaron Discovery & Early Development, West Hill Innovation Park, Hertford Road, Hoddesdon, Hertfordshire EN11 9FH, UK., Wang S; Pharmaron Discovery & Early Development, West Hill Innovation Park, Hertford Road, Hoddesdon, Hertfordshire EN11 9FH, UK., Maclean J; Pharmaron Discovery & Early Development, West Hill Innovation Park, Hertford Road, Hoddesdon, Hertfordshire EN11 9FH, UK., Zanelli U; Galderma SA, Av. d'Ouchy 4, 1006 Lausanne, Switzerland., Taylor S; Pharmaron Discovery & Early Development, West Hill Innovation Park, Hertford Road, Hoddesdon, Hertfordshire EN11 9FH, UK., Foote K; Pharmaron Discovery & Early Development, West Hill Innovation Park, Hertford Road, Hoddesdon, Hertfordshire EN11 9FH, UK., Hacini-Rachinel F; Galderma SA, Av. d'Ouchy 4, 1006 Lausanne, Switzerland., Nicodeme E; Galderma SA, Av. d'Ouchy 4, 1006 Lausanne, Switzerland., Julia V; Galderma SA, Av. d'Ouchy 4, 1006 Lausanne, Switzerland.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Mar 01; Vol. 100, pp. 129630. Date of Electronic Publication: 2024 Feb 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE; PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1464-3405
DOI:10.1016/j.bmcl.2024.129630