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Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease.

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Title: Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease.
Authors: Yang HS; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Yau WW; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Carlyle BC; Harvard Medical School, Boston, MA 02115, USA.; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.; Department of Physiology, Anatomy and Genetics, Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3PT, UK., Trombetta BA; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA., Zhang C; Harvard Medical School, Boston, MA 02115, USA.; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.; Genetics and Aging Research Unit, McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Shirzadi Z; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Harvard Medical School, Boston, MA 02115, USA., Schultz AP; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Harvard Medical School, Boston, MA 02115, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA., Pruzin JJ; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Banner Alzheimer's Institute, Phoenix, AZ 85006, USA., Fitzpatrick CD; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA., Kirn DR; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA., Rabin JS; Harquail Centre for Neuromodulation and Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.; Department of Medicine, Rehabilitation Sciences Institute, University of Toronto, Toronto, ON M5G 1V7, Canada., Buckley RF; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37212, USA., Rentz DM; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Tanzi RE; Harvard Medical School, Boston, MA 02115, USA.; Genetics and Aging Research Unit, McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Johnson KA; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA., Sperling RA; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA., Arnold SE; Harvard Medical School, Boston, MA 02115, USA.; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA., Chhatwal JP; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.
Source: Brain : a journal of neurology [Brain] 2024 Jun 03; Vol. 147 (6), pp. 2158-2168.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Yang+HS%22">Yang HS</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Yau+WW%22">Yau WW</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Carlyle+BC%22">Carlyle BC</searchLink>; Harvard Medical School, Boston, MA 02115, USA.; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.; Department of Physiology, Anatomy and Genetics, Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3PT, UK.<br /><searchLink fieldCode="AU" term="%22Trombetta+BA%22">Trombetta BA</searchLink>; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Harvard Medical School, Boston, MA 02115, USA.; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.; Genetics and Aging Research Unit, McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Shirzadi+Z%22">Shirzadi Z</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Schultz+AP%22">Schultz AP</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Harvard Medical School, Boston, MA 02115, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Pruzin+JJ%22">Pruzin JJ</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Banner Alzheimer's Institute, Phoenix, AZ 85006, USA.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+CD%22">Fitzpatrick CD</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Kirn+DR%22">Kirn DR</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Rabin+JS%22">Rabin JS</searchLink>; Harquail Centre for Neuromodulation and Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.; Department of Medicine, Rehabilitation Sciences Institute, University of Toronto, Toronto, ON M5G 1V7, Canada.<br /><searchLink fieldCode="AU" term="%22Buckley+RF%22">Buckley RF</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Hohman+TJ%22">Hohman TJ</searchLink>; Vanderbilt Memory and Alzheimer's Center, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37212, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37212, USA.<br /><searchLink fieldCode="AU" term="%22Rentz+DM%22">Rentz DM</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Tanzi+RE%22">Tanzi RE</searchLink>; Harvard Medical School, Boston, MA 02115, USA.; Genetics and Aging Research Unit, McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+KA%22">Johnson KA</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Sperling+RA%22">Sperling RA</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Arnold+SE%22">Arnold SE</searchLink>; Harvard Medical School, Boston, MA 02115, USA.; Alzheimer's Clinical and Translational Research Unit, Department of Neurology, Massachusetts General Hospital, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Chhatwal+JP%22">Chhatwal JP</searchLink>; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA.
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        Value: 10.1093/brain/awae034
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              Text: 2024 Jun 03
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