Health-related quality of life in patients with newly diagnosed advanced ovarian cancer treated with niraparib vs placebo: Results from the phase 3 randomized PRIMA/ENGOT-OV26/GOG-3012 trial.

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Title: Health-related quality of life in patients with newly diagnosed advanced ovarian cancer treated with niraparib vs placebo: Results from the phase 3 randomized PRIMA/ENGOT-OV26/GOG-3012 trial.
Authors: Pothuri B; GOG Foundation and Departments of Obstetrics/Gynecology and Medicine, Division of Gynecologic Oncology, Laura & Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA. Electronic address: Bhavana.pothuri@nyulangone.org., Han S; Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium., Chase DM; Department of Obstetrics and Gynecology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA., Heitz F; AGO Study Group, Department for Gynaecology and Gynaecologic Oncology, Kliniken Essen- Mitte, Essen, Germany; Department of Gynaecology, Charité-Universitätsmedizin Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; and Berlin Institute of Health, Berlin, Germany., Burger RA; Department of Obstetrics & Gynecology, University of Pennsylvania, Philadelphia, PA, USA., Gaba L; Medical Oncology Department, Hospital Clinic de Barcelona, Translational Genomics and Targeted Therapies in Solid Tumors, Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain., Van Le L; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Guerra E; Medical Oncology Department, Breast and Gynaecological Cancer Unit, Hospital Ramón y Cajal, Madrid, Spain., Bender D; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA., Korach J; Gynecologic Oncology Department, The Chaim Sheba Medical Center, Sackler Medical School, Tel Aviv University, Ramat Gan, Israel., Cloven N; Texas Oncology, Fort Worth, TX, USA., Churruca C; Medical Oncology Department, Hospital Universitario Donostia, San Sebastian, Spain., Follana P; Groupe d'Investigateurs Nationaux pour l'Etude des Cancers Ovariens (GINECO) and Département D'oncologie Médicale, Centre Antoine Lacassagne, Nice, France., DiSilvestro P; Department of Obstetrics and Gynecology, Women and Infants Hospital/Alpert School of Medicine at Brown University, Providence, RI, USA., Baurain JF; Medical Oncology Departement, Université Catholique de Louvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium., Jardon K; Department of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada., Pisano C; Department of Urology and Gynaecology, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Naples, Italy., Peen U; Herlev University Hospital, Herlev, Denmark., Mäenpää J; NSGO and Tampere University, Tampere, Finland., Gupta D; GSK, Waltham, MA, USA., Bacqué E; GSK, Waltham, MA, USA., Li Y; GSK, Waltham, MA, USA., Compton N; GSK, London, United Kingdom., Antonova J; GSK, Waltham, MA, USA., Monk BJ; HonorHealth Research Institute, University of Arizona College of Medicine, Phoenix, and Creighton University School of Medicine, Phoenix, AZ, USA., González-Martín A; Medical Oncology Department and Program in Solid Tumours - CIMA, Cancer Center Clínica Universidad de Navarra, Grupo Español de Investigación en Cáncer de Ovario (GEICO), Madrid, Spain.
Source: Gynecologic oncology [Gynecol Oncol] 2024 May; Vol. 184, pp. 168-177. Date of Electronic Publication: 2024 Feb 06.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE
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  Data: Health-related quality of life in patients with newly diagnosed advanced ovarian cancer treated with niraparib vs placebo: Results from the phase 3 randomized PRIMA/ENGOT-OV26/GOG-3012 trial.
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  Data: <searchLink fieldCode="AU" term="%22Pothuri+B%22">Pothuri B</searchLink>; GOG Foundation and Departments of Obstetrics/Gynecology and Medicine, Division of Gynecologic Oncology, Laura & Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA. Electronic address: Bhavana.pothuri@nyulangone.org.<br /><searchLink fieldCode="AU" term="%22Han+S%22">Han S</searchLink>; Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Chase+DM%22">Chase DM</searchLink>; Department of Obstetrics and Gynecology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Heitz+F%22">Heitz F</searchLink>; AGO Study Group, Department for Gynaecology and Gynaecologic Oncology, Kliniken Essen- Mitte, Essen, Germany; Department of Gynaecology, Charité-Universitätsmedizin Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; and Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Burger+RA%22">Burger RA</searchLink>; Department of Obstetrics & Gynecology, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gaba+L%22">Gaba L</searchLink>; Medical Oncology Department, Hospital Clinic de Barcelona, Translational Genomics and Targeted Therapies in Solid Tumors, Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Van+Le+L%22">Van Le L</searchLink>; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Guerra+E%22">Guerra E</searchLink>; Medical Oncology Department, Breast and Gynaecological Cancer Unit, Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bender+D%22">Bender D</searchLink>; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Korach+J%22">Korach J</searchLink>; Gynecologic Oncology Department, The Chaim Sheba Medical Center, Sackler Medical School, Tel Aviv University, Ramat Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Cloven+N%22">Cloven N</searchLink>; Texas Oncology, Fort Worth, TX, USA.<br /><searchLink fieldCode="AU" term="%22Churruca+C%22">Churruca C</searchLink>; Medical Oncology Department, Hospital Universitario Donostia, San Sebastian, Spain.<br /><searchLink fieldCode="AU" term="%22Follana+P%22">Follana P</searchLink>; Groupe d'Investigateurs Nationaux pour l'Etude des Cancers Ovariens (GINECO) and Département D'oncologie Médicale, Centre Antoine Lacassagne, Nice, France.<br /><searchLink fieldCode="AU" term="%22DiSilvestro+P%22">DiSilvestro P</searchLink>; Department of Obstetrics and Gynecology, Women and Infants Hospital/Alpert School of Medicine at Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Baurain+JF%22">Baurain JF</searchLink>; Medical Oncology Departement, Université Catholique de Louvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Jardon+K%22">Jardon K</searchLink>; Department of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Pisano+C%22">Pisano C</searchLink>; Department of Urology and Gynaecology, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Peen+U%22">Peen U</searchLink>; Herlev University Hospital, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Mäenpää+J%22">Mäenpää J</searchLink>; NSGO and Tampere University, Tampere, Finland.<br /><searchLink fieldCode="AU" term="%22Gupta+D%22">Gupta D</searchLink>; GSK, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bacqué+E%22">Bacqué E</searchLink>; GSK, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; GSK, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Compton+N%22">Compton N</searchLink>; GSK, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Antonova+J%22">Antonova J</searchLink>; GSK, Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Monk+BJ%22">Monk BJ</searchLink>; HonorHealth Research Institute, University of Arizona College of Medicine, Phoenix, and Creighton University School of Medicine, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22González-Martín+A%22">González-Martín A</searchLink>; Medical Oncology Department and Program in Solid Tumours - CIMA, Cancer Center Clínica Universidad de Navarra, Grupo Español de Investigación en Cáncer de Ovario (GEICO), Madrid, Spain.
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  Data: <searchLink fieldCode="JN" term="%220365304%22">Gynecologic oncology</searchLink> [Gynecol Oncol] 2024 May; Vol. 184, pp. 168-177. <i>Date of Electronic Publication: </i>2024 Feb 06.
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  Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0365304 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-6859 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200908258%22">00908258 </searchLink><i>NLM ISO Abbreviation: </i>Gynecol Oncol <i>Subsets: </i>MEDLINE
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