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FDA-approved disulfiram as a novel treatment for aggressive leukemia.

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Title: FDA-approved disulfiram as a novel treatment for aggressive leukemia.
Authors: Karsa M; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Xiao L; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Ronca E; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Bongers A; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Spurling D; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Karsa A; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Cantilena S; Cancer Section, Development Biology and Cancer Programme, UCL GOS Institute of Child Health, London, UK., Mariana A; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Failes TW; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Arndt GM; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Cheung LC; Leukemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; Curtin Health Innovation Research Institute, Curtin University, Perth, WA, Australia., Kotecha RS; Leukemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia.; Division of Paediatrics, School of Medicine, University of Western Australia, Perth, WA, Australia., Sutton R; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Lock RB; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, Australia., Williams O; Cancer Section, Development Biology and Cancer Programme, UCL GOS Institute of Child Health, London, UK., de Boer J; Cancer Section, Development Biology and Cancer Programme, UCL GOS Institute of Child Health, London, UK., Haber M; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Norris MD; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, Australia., Henderson MJ; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Somers K; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia. ksomers@ccia.org.au.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia. ksomers@ccia.org.au.
Source: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2024 Apr; Vol. 102 (4), pp. 507-519. Date of Electronic Publication: 2024 Feb 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9504370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1440 (Electronic) Linking ISSN: 09462716 NLM ISO Abbreviation: J Mol Med (Berl) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FDA-approved disulfiram as a novel treatment for aggressive leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Karsa+M%22">Karsa M</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Xiao+L%22">Xiao L</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Ronca+E%22">Ronca E</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Bongers+A%22">Bongers A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Spurling+D%22">Spurling D</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Karsa+A%22">Karsa A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Cantilena+S%22">Cantilena S</searchLink>; Cancer Section, Development Biology and Cancer Programme, UCL GOS Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Mariana+A%22">Mariana A</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Failes+TW%22">Failes TW</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Arndt+GM%22">Arndt GM</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Cheung+LC%22">Cheung LC</searchLink>; Leukemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; Curtin Health Innovation Research Institute, Curtin University, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Kotecha+RS%22">Kotecha RS</searchLink>; Leukemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia.; Curtin Medical School, Curtin University, Perth, WA, Australia.; Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, WA, Australia.; Division of Paediatrics, School of Medicine, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Sutton+R%22">Sutton R</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Lock+RB%22">Lock RB</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Williams+O%22">Williams O</searchLink>; Cancer Section, Development Biology and Cancer Programme, UCL GOS Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22de+Boer+J%22">de Boer J</searchLink>; Cancer Section, Development Biology and Cancer Programme, UCL GOS Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Haber+M%22">Haber M</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Norris+MD%22">Norris MD</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Henderson+MJ%22">Henderson MJ</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Somers+K%22">Somers K</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia. ksomers@ccia.org.au.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia. ksomers@ccia.org.au.
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  Data: <searchLink fieldCode="JN" term="%229504370%22">Journal of molecular medicine (Berlin, Germany)</searchLink> [J Mol Med (Berl)] 2024 Apr; Vol. 102 (4), pp. 507-519. <i>Date of Electronic Publication: </i>2024 Feb 13.
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