Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response.

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Title: Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response.
Authors: Yalaz C; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK. cerenyalaz@gmail.com., Bridges E; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK., Alham NK; Department of Engineering Science, Institute of Biomedical Engineering (IBME), University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Zois CE; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK., Chen J; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Bensaad K; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK., Miar A; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Pires E; Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK., Muschel RJ; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., McCullagh JSO; Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK., Harris AL; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.
Source: Cancer & metabolism [Cancer Metab] 2024 Feb 13; Vol. 12 (1), pp. 5. Date of Electronic Publication: 2024 Feb 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101607582 Publication Model: Electronic Cited Medium: Print ISSN: 2049-3002 (Print) Linking ISSN: 20493002 NLM ISO Abbreviation: Cancer Metab Subsets: PubMed not MEDLINE
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  Data: Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response.
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  Data: <searchLink fieldCode="AU" term="%22Yalaz+C%22">Yalaz C</searchLink>; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK. cerenyalaz@gmail.com.<br /><searchLink fieldCode="AU" term="%22Bridges+E%22">Bridges E</searchLink>; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.<br /><searchLink fieldCode="AU" term="%22Alham+NK%22">Alham NK</searchLink>; Department of Engineering Science, Institute of Biomedical Engineering (IBME), University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Zois+CE%22">Zois CE</searchLink>; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Bensaad+K%22">Bensaad K</searchLink>; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.<br /><searchLink fieldCode="AU" term="%22Miar+A%22">Miar A</searchLink>; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Pires+E%22">Pires E</searchLink>; Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK.<br /><searchLink fieldCode="AU" term="%22Muschel+RJ%22">Muschel RJ</searchLink>; Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22McCullagh+JSO%22">McCullagh JSO</searchLink>; Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK.<br /><searchLink fieldCode="AU" term="%22Harris+AL%22">Harris AL</searchLink>; Molecular Oncology Laboratories, Department of Medical Oncology, John Radcliffe Hospital, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.
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  Data: <searchLink fieldCode="JN" term="%22101607582%22">Cancer & metabolism</searchLink> [Cancer Metab] 2024 Feb 13; Vol. 12 (1), pp. 5. <i>Date of Electronic Publication: </i>2024 Feb 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101607582 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2049-3002 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220493002%22">20493002 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Metab <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2024 Feb 13
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