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Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.

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Title: Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
Authors: Poudel YB; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., He L; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Cox M; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Zhang Q; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Johnson WL; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Cong Q; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Cheng H; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Chowdari NS; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Tarby C; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Donnell AF; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Broekema M; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., O'Malley DP; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Zhang Y; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., A M Subbaiah M; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India., Kumar BV; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India., Subramani L; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India., Wang B; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Li YX; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States., Sivaprakasam P; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Critton D; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Mulligan D; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Sandhu B; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Xie C; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Ramakrishnan R; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Nagar J; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India., Dudhgaonkar S; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India., Oderinde MS; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Murtaza A; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Schieven GL; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Mathur A; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Gavai AV; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Vite G; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States., Gangwar S; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Jan 08; Vol. 15 (2), pp. 181-188. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
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  Data: <searchLink fieldCode="AU" term="%22Poudel+YB%22">Poudel YB</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22He+L%22">He L</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Cox+M%22">Cox M</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Johnson+WL%22">Johnson WL</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Cong+Q%22">Cong Q</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Cheng+H%22">Cheng H</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Chowdari+NS%22">Chowdari NS</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Tarby+C%22">Tarby C</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Donnell+AF%22">Donnell AF</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Broekema+M%22">Broekema M</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22O'Malley+DP%22">O'Malley DP</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22A+M+Subbaiah+M%22">A M Subbaiah M</searchLink>; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India.<br /><searchLink fieldCode="AU" term="%22Kumar+BV%22">Kumar BV</searchLink>; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India.<br /><searchLink fieldCode="AU" term="%22Subramani+L%22">Subramani L</searchLink>; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Li+YX%22">Li YX</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.<br /><searchLink fieldCode="AU" term="%22Sivaprakasam+P%22">Sivaprakasam P</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Critton+D%22">Critton D</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Mulligan+D%22">Mulligan D</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Sandhu+B%22">Sandhu B</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Xie+C%22">Xie C</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Ramakrishnan+R%22">Ramakrishnan R</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Nagar+J%22">Nagar J</searchLink>; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India.<br /><searchLink fieldCode="AU" term="%22Dudhgaonkar+S%22">Dudhgaonkar S</searchLink>; The Biocon Bristol Myers Squibb Research Center (BBRC), Bangalore 560099, India.<br /><searchLink fieldCode="AU" term="%22Oderinde+MS%22">Oderinde MS</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Murtaza+A%22">Murtaza A</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Schieven+GL%22">Schieven GL</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Mathur+A%22">Mathur A</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Gavai+AV%22">Gavai AV</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Vite+G%22">Vite G</searchLink>; Bristol-Myers Squibb Research & Development, Princeton, New Jersey 08543, United States.<br /><searchLink fieldCode="AU" term="%22Gangwar+S%22">Gangwar S</searchLink>; Bristol-Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States.
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  Data: <searchLink fieldCode="JN" term="%22101521073%22">ACS medicinal chemistry letters</searchLink> [ACS Med Chem Lett] 2024 Jan 08; Vol. 15 (2), pp. 181-188. <i>Date of Electronic Publication: </i>2024 Jan 08 (<i>Print Publication: </i>2024).
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