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Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas.

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Title: Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas.
Authors: Burger BT; Genus plc Research and Development, DeForest, Wisconsin, USA., Beaton BP; Genus plc Research and Development, DeForest, Wisconsin, USA., Campbell MA; Genus plc Research and Development, DeForest, Wisconsin, USA., Brett BT; Genus plc Research and Development, DeForest, Wisconsin, USA., Rohrer MS; Genus plc Research and Development, DeForest, Wisconsin, USA., Plummer S; Genus plc Research and Development, DeForest, Wisconsin, USA., Barnes D; Genus plc Research and Development, DeForest, Wisconsin, USA., Jiang K; Genus plc Research and Development, DeForest, Wisconsin, USA., Naswa S; Genus plc Research and Development, DeForest, Wisconsin, USA., Lange J; Genus plc Research and Development, DeForest, Wisconsin, USA., Ott A; Genus plc Research and Development, DeForest, Wisconsin, USA., Alger E; Genus plc Research and Development, DeForest, Wisconsin, USA., Rincon G; Genus plc Research and Development, DeForest, Wisconsin, USA., Rounsley S; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Inari Agriculture, West Lafayette, IN, USA., Betthauser J; Genus plc Research and Development, DeForest, Wisconsin, USA., Mtango NR; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Colossal Biosciences, Dallas, TX, USA., Benne JA; Genus plc Research and Development, DeForest, Wisconsin, USA., Hammerand J; Genus plc Research and Development, DeForest, Wisconsin, USA., Durfee CJ; Genus plc Research and Development, DeForest, Wisconsin, USA., Rotolo ML; PIC, Hendersonville, Tennessee, USA.; Current address: National Pork Board, Des Moines, IA, USA., Cameron P; Caribou Biosciences, Berkeley, California, USA.; Current address: Profluent Bio, Berkeley, CA, USA., Lied AM; Caribou Biosciences, Berkeley, California, USA., Irby MJ; Caribou Biosciences, Berkeley, California, USA.; Current address: Prime Medicine, Cambridge, MA, USA., Nyer DB; Caribou Biosciences, Berkeley, California, USA.; Current address: Clade Therapeutics, Boston, MA, USA., Fuller CK; Caribou Biosciences, Berkeley, California, USA., Gradia S; Caribou Biosciences, Berkeley, California, USA., Kanner SB; Caribou Biosciences, Berkeley, California, USA., Park KE; RenOVAte Biosciences, Reisterstown, Maryland, USA., Waters J; RenOVAte Biosciences, Reisterstown, Maryland, USA., Simpson S; RenOVAte Biosciences, Reisterstown, Maryland, USA., Telugu BP; RenOVAte Biosciences, Reisterstown, Maryland, USA., Salgado BC; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA., Brandariz-Nuñez A; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA., Rowland RRR; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA., Culbertson M; PIC, Hendersonville, Tennessee, USA., Rice E; Genus plc Research and Development, DeForest, Wisconsin, USA., Cigan AM; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Cobb-Vantress, Siloam Springs, AR, USA.
Source: The CRISPR journal [CRISPR J] 2024 Feb; Vol. 7 (1), pp. 12-28.
Publication Type: Journal Article
Journal Info: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101738191 Publication Model: Print Cited Medium: Internet ISSN: 2573-1602 (Electronic) Linking ISSN: 25731599 NLM ISO Abbreviation: CRISPR J Subsets: MEDLINE
Database: MEDLINE Ultimate
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IllustrationInfo
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  Data: Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas.
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Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Naswa+S%22">Naswa S</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Lange+J%22">Lange J</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Ott+A%22">Ott A</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Alger+E%22">Alger E</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Rincon+G%22">Rincon G</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Rounsley+S%22">Rounsley S</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Inari Agriculture, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Betthauser+J%22">Betthauser J</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Mtango+NR%22">Mtango NR</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Colossal Biosciences, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Benne+JA%22">Benne JA</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Hammerand+J%22">Hammerand J</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Durfee+CJ%22">Durfee CJ</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Rotolo+ML%22">Rotolo ML</searchLink>; PIC, Hendersonville, Tennessee, USA.; Current address: National Pork Board, Des Moines, IA, USA.<br /><searchLink fieldCode="AU" term="%22Cameron+P%22">Cameron P</searchLink>; Caribou Biosciences, Berkeley, California, USA.; Current address: Profluent Bio, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lied+AM%22">Lied AM</searchLink>; Caribou Biosciences, Berkeley, California, USA.<br /><searchLink fieldCode="AU" term="%22Irby+MJ%22">Irby MJ</searchLink>; Caribou Biosciences, Berkeley, California, USA.; Current address: Prime Medicine, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nyer+DB%22">Nyer DB</searchLink>; Caribou Biosciences, Berkeley, California, USA.; Current address: Clade Therapeutics, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fuller+CK%22">Fuller CK</searchLink>; Caribou Biosciences, Berkeley, California, USA.<br /><searchLink fieldCode="AU" term="%22Gradia+S%22">Gradia S</searchLink>; Caribou Biosciences, Berkeley, California, USA.<br /><searchLink fieldCode="AU" term="%22Kanner+SB%22">Kanner SB</searchLink>; Caribou Biosciences, Berkeley, California, USA.<br /><searchLink fieldCode="AU" term="%22Park+KE%22">Park KE</searchLink>; RenOVAte Biosciences, Reisterstown, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Waters+J%22">Waters J</searchLink>; RenOVAte Biosciences, Reisterstown, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Simpson+S%22">Simpson S</searchLink>; RenOVAte Biosciences, Reisterstown, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Telugu+BP%22">Telugu BP</searchLink>; RenOVAte Biosciences, Reisterstown, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Salgado+BC%22">Salgado BC</searchLink>; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Brandariz-Nuñez+A%22">Brandariz-Nuñez A</searchLink>; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Rowland+RRR%22">Rowland RRR</searchLink>; Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Culbertson+M%22">Culbertson M</searchLink>; PIC, Hendersonville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Rice+E%22">Rice E</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Cigan+AM%22">Cigan AM</searchLink>; Genus plc Research and Development, DeForest, Wisconsin, USA.; Current address: Cobb-Vantress, Siloam Springs, AR, USA.
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  Data: <searchLink fieldCode="JN" term="%22101738191%22">The CRISPR journal</searchLink> [CRISPR J] 2024 Feb; Vol. 7 (1), pp. 12-28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mary+Ann+Liebert%2C+Inc%22">Mary Ann Liebert, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101738191 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2573-1602 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225731599%22">25731599 </searchLink><i>NLM ISO Abbreviation: </i>CRISPR J <i>Subsets: </i>MEDLINE
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