Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals.

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Title: Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals.
Authors: Cohen AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally., Keeffe JR; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally., Schiepers A; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, 10065, USA., Dross SE; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.; National Primate Research Center, Seattle, WA 98121, USA., Greaney AJ; Medical Scientist Training Program, University of Washington, Seattle, WA 98195, USA., Rorick AV; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Gao H; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Gnanapragasam PNP; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Fan C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., West AP Jr; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Ramsingh AI; Creative BioSolutions, LLC, Miami, FL, 33131, USA., Erasmus JH; HDT Bio, Seattle, WA, 98109, USA., Pata JD; Wadsworth Center, New York State Department of Health and Department of Biomedical Sciences, University at Albany, Albany, NY, 12201, USA., Muramatsu H; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Pardi N; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lin PJC; Acuitas Therapeutics, Vancouver, BC V6T 1Z3, Canada., Baxter S; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Cruz R; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Quintanar-Audelo M; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.; Present address: Centre for Inflammation Research and Institute of Regeneration and Repair, The University of Edinburgh, Edinburgh, EH16 4UU, UK., Robb E; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Serrano-Amatriain C; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Magneschi L; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Fotheringham IG; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK., Fuller DH; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.; National Primate Research Center, Seattle, WA 98121, USA., Victora GD; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, 10065, USA., Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; Lead contact.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 22. Date of Electronic Publication: 2024 May 22.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
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  Data: Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals.
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  Data: <searchLink fieldCode="AU" term="%22Cohen+AA%22">Cohen AA</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Keeffe+JR%22">Keeffe JR</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Schiepers+A%22">Schiepers A</searchLink>; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, 10065, USA.<br /><searchLink fieldCode="AU" term="%22Dross+SE%22">Dross SE</searchLink>; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.; National Primate Research Center, Seattle, WA 98121, USA.<br /><searchLink fieldCode="AU" term="%22Greaney+AJ%22">Greaney AJ</searchLink>; Medical Scientist Training Program, University of Washington, Seattle, WA 98195, USA.<br /><searchLink fieldCode="AU" term="%22Rorick+AV%22">Rorick AV</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Gao+H%22">Gao H</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Gnanapragasam+PNP%22">Gnanapragasam PNP</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Fan+C%22">Fan C</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22West+AP+Jr%22">West AP Jr</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Ramsingh+AI%22">Ramsingh AI</searchLink>; Creative BioSolutions, LLC, Miami, FL, 33131, USA.<br /><searchLink fieldCode="AU" term="%22Erasmus+JH%22">Erasmus JH</searchLink>; HDT Bio, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Pata+JD%22">Pata JD</searchLink>; Wadsworth Center, New York State Department of Health and Department of Biomedical Sciences, University at Albany, Albany, NY, 12201, USA.<br /><searchLink fieldCode="AU" term="%22Muramatsu+H%22">Muramatsu H</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Pardi+N%22">Pardi N</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Lin+PJC%22">Lin PJC</searchLink>; Acuitas Therapeutics, Vancouver, BC V6T 1Z3, Canada.<br /><searchLink fieldCode="AU" term="%22Baxter+S%22">Baxter S</searchLink>; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.<br /><searchLink fieldCode="AU" term="%22Cruz+R%22">Cruz R</searchLink>; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.<br /><searchLink fieldCode="AU" term="%22Quintanar-Audelo+M%22">Quintanar-Audelo M</searchLink>; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.; Present address: Centre for Inflammation Research and Institute of Regeneration and Repair, The University of Edinburgh, Edinburgh, EH16 4UU, UK.<br /><searchLink fieldCode="AU" term="%22Robb+E%22">Robb E</searchLink>; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.<br /><searchLink fieldCode="AU" term="%22Serrano-Amatriain+C%22">Serrano-Amatriain C</searchLink>; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.<br /><searchLink fieldCode="AU" term="%22Magneschi+L%22">Magneschi L</searchLink>; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.<br /><searchLink fieldCode="AU" term="%22Fotheringham+IG%22">Fotheringham IG</searchLink>; Ingenza Ltd, Roslin Innovation Centre, Charnock Bradley Building, Roslin, EH25 9RG, UK.<br /><searchLink fieldCode="AU" term="%22Fuller+DH%22">Fuller DH</searchLink>; Department of Microbiology, University of Washington, Seattle, WA 98195, USA.; National Primate Research Center, Seattle, WA 98121, USA.<br /><searchLink fieldCode="AU" term="%22Victora+GD%22">Victora GD</searchLink>; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, 10065, USA.<br /><searchLink fieldCode="AU" term="%22Bjorkman+PJ%22">Bjorkman PJ</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; Lead contact.
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