Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo.
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| Title: | Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo. |
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| Authors: | Mugnaini C; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy., Brizzi A; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy., Paolino M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy., Scarselli E; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy., Castelli R; Department of Food and Drug, University of Parma, 43124 Parma, Italy., de Candia M; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy., Gambacorta N; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy., Nicolotti O; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy., Kostrzewa M; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy., Kumar P; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy., Mahmoud AM; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy., Borgonetti V; Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology and Toxicology, University of Florence, 50121 Florence, Italy., Iannotta M; Department of Experimental Medicine, Division of Pharmacology, University of Campania 'L. Vanvitelli″, 80138 Naples, Italy., Morace A; Department of Experimental Medicine, Division of Pharmacology, University of Campania 'L. Vanvitelli″, 80138 Naples, Italy., Galeotti N; Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology and Toxicology, University of Florence, 50121 Florence, Italy., Maione S; Department of Experimental Medicine, Division of Pharmacology, University of Campania 'L. Vanvitelli″, 80138 Naples, Italy., Altomare CD; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy., Ligresti A; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy., Corelli F; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. |
| Source: | ACS chemical neuroscience [ACS Chem Neurosci] 2024 Mar 06; Vol. 15 (5), pp. 955-971. Date of Electronic Publication: 2024 Feb 19. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38372253 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Mugnaini+C%22">Mugnaini C</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Brizzi+A%22">Brizzi A</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Paolino+M%22">Paolino M</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Scarselli+E%22">Scarselli E</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Castelli+R%22">Castelli R</searchLink>; Department of Food and Drug, University of Parma, 43124 Parma, Italy.<br /><searchLink fieldCode="AU" term="%22de+Candia+M%22">de Candia M</searchLink>; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Gambacorta+N%22">Gambacorta N</searchLink>; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Nicolotti+O%22">Nicolotti O</searchLink>; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Kostrzewa+M%22">Kostrzewa M</searchLink>; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy.<br /><searchLink fieldCode="AU" term="%22Kumar+P%22">Kumar P</searchLink>; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy.<br /><searchLink fieldCode="AU" term="%22Mahmoud+AM%22">Mahmoud AM</searchLink>; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy.<br /><searchLink fieldCode="AU" term="%22Borgonetti+V%22">Borgonetti V</searchLink>; Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology and Toxicology, University of Florence, 50121 Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Iannotta+M%22">Iannotta M</searchLink>; Department of Experimental Medicine, Division of Pharmacology, University of Campania 'L. Vanvitelli″, 80138 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Morace+A%22">Morace A</searchLink>; Department of Experimental Medicine, Division of Pharmacology, University of Campania 'L. Vanvitelli″, 80138 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Galeotti+N%22">Galeotti N</searchLink>; Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), Section of Pharmacology and Toxicology, University of Florence, 50121 Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Maione+S%22">Maione S</searchLink>; Department of Experimental Medicine, Division of Pharmacology, University of Campania 'L. Vanvitelli″, 80138 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Altomare+CD%22">Altomare CD</searchLink>; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, 70125 Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Ligresti+A%22">Ligresti A</searchLink>; Institute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Naples ,Italy.<br /><searchLink fieldCode="AU" term="%22Corelli+F%22">Corelli F</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101525337%22">ACS chemical neuroscience</searchLink> [ACS Chem Neurosci] 2024 Mar 06; Vol. 15 (5), pp. 955-971. <i>Date of Electronic Publication: </i>2024 Feb 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101525337 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1948-7193 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219487193%22">19487193 </searchLink><i>NLM ISO Abbreviation: </i>ACS Chem Neurosci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38372253 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acschemneuro.3c00656 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 955 Titles: – TitleFull: Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mugnaini C – PersonEntity: Name: NameFull: Brizzi A – PersonEntity: Name: NameFull: Paolino M – PersonEntity: Name: NameFull: Scarselli E – PersonEntity: Name: NameFull: Castelli R – PersonEntity: Name: NameFull: de Candia M – PersonEntity: Name: NameFull: Gambacorta N – PersonEntity: Name: NameFull: Nicolotti O – PersonEntity: Name: NameFull: Kostrzewa M – PersonEntity: Name: NameFull: Kumar P – PersonEntity: Name: NameFull: Mahmoud AM – PersonEntity: Name: NameFull: Borgonetti V – PersonEntity: Name: NameFull: Iannotta M – PersonEntity: Name: NameFull: Morace A – PersonEntity: Name: NameFull: Galeotti N – PersonEntity: Name: NameFull: Maione S – PersonEntity: Name: NameFull: Altomare CD – PersonEntity: Name: NameFull: Ligresti A – PersonEntity: Name: NameFull: Corelli F IsPartOfRelationships: – BibEntity: Dates: – D: 06 M: 03 Text: 2024 Mar 06 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1948-7193 Numbering: – Type: volume Value: 15 – Type: issue Value: 5 Titles: – TitleFull: ACS chemical neuroscience Type: main |
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