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Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer.

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Title: Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer.
Authors: Wallace-Povirk A; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., O'Connor C; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Dekhne AS; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Bao X; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Nayeen MJ; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania., Schneider M; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Katinas JM; Department of Chemistry, Indiana University, Bloomington, Indiana., Wong-Roushar J; Department of Chemistry, Indiana University, Bloomington, Indiana., Kim S; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Polin L; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Li J; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Back JB; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Dann CE 3rd; Department of Chemistry, Indiana University, Bloomington, Indiana., Gangjee A; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania., Hou Z; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Matherly LH; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Jun 04; Vol. 23 (6), pp. 809-822.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wallace-Povirk+A%22">Wallace-Povirk A</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22O'Connor+C%22">O'Connor C</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Dekhne+AS%22">Dekhne AS</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Bao+X%22">Bao X</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Nayeen+MJ%22">Nayeen MJ</searchLink>; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Schneider+M%22">Schneider M</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Katinas+JM%22">Katinas JM</searchLink>; Department of Chemistry, Indiana University, Bloomington, Indiana.<br /><searchLink fieldCode="AU" term="%22Wong-Roushar+J%22">Wong-Roushar J</searchLink>; Department of Chemistry, Indiana University, Bloomington, Indiana.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Polin+L%22">Polin L</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Back+JB%22">Back JB</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Dann+CE+3rd%22">Dann CE 3rd</searchLink>; Department of Chemistry, Indiana University, Bloomington, Indiana.<br /><searchLink fieldCode="AU" term="%22Gangjee+A%22">Gangjee A</searchLink>; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hou+Z%22">Hou Z</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Matherly+LH%22">Matherly LH</searchLink>; Department of Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan.
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