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Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests.

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Title: Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests.
Authors: Barthélemy NR; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA., Salvadó G; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC), Washington University School of Medicine, St. Louis, MO, USA., He Y; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Collij LE; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands., Saef B; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Henson RL; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Chen CD; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Gordon BA; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Li Y; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Division of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., La Joie R; Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Benzinger TLS; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC), Washington University School of Medicine, St. Louis, MO, USA., Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund University, Lund, Sweden., Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Ossenkoppele R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands., Rabinovici GD; Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA., Stomrud E; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Bateman RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC), Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se.
Source: Nature medicine [Nat Med] 2024 Apr; Vol. 30 (4), pp. 1085-1095. Date of Electronic Publication: 2024 Feb 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
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  Data: Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests.
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  Data: <searchLink fieldCode="AU" term="%22Barthélemy+NR%22">Barthélemy NR</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Salvadó+G%22">Salvadó G</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Schindler+SE%22">Schindler SE</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC), Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Janelidze+S%22">Janelidze S</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Collij+LE%22">Collij LE</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Saef+B%22">Saef B</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Henson+RL%22">Henson RL</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Chen+CD%22">Chen CD</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+BA%22">Gordon BA</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Division of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22La+Joie+R%22">La Joie R</searchLink>; Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Benzinger+TLS%22">Benzinger TLS</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC), Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Mattsson-Carlgren+N%22">Mattsson-Carlgren N</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Palmqvist+S%22">Palmqvist S</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Ossenkoppele+R%22">Ossenkoppele R</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rabinovici+GD%22">Rabinovici GD</searchLink>; Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stomrud+E%22">Stomrud E</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Bateman+RJ%22">Bateman RJ</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Tracy Family Stable Isotope Labeling Quantitation (SILQ) Center, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC), Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se.
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