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Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease.

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Title: Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease.
Authors: Mudhasani RR; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Golden JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Adam GC; Quantitative Biosciences, Merck & Co. Inc., Rahway, New Jersey, USA., Hartingh TJ; Discovery Chemistry, Merck & Co. Inc., Rahway, New Jersey, USA., Kota KP; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Ordonez D; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Quackenbush CR; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Tran JP; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Cline C; Pathology, Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Williams JA; Pathology, Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Zeng X; Pathology, Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Olsen DB; Infectious Diseases and Vaccines, Merck & Co. Inc., Rahway, New Jersey, USA., Lieberman LA; Discovery Immunology, Merck & Co. Inc., Rahway, New Jersey, USA., Boyce C; Discovery Pharmaceutical Sciences, Merck & Co. Inc., Rahway, New Jersey, USA., Ginnetti A; Discovery Chemistry, Merck & Co. Inc., Rahway, New Jersey, USA., Meinig JM; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Panchal RG; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA., Mucker EM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Source: Microbiology spectrum [Microbiol Spectr] 2024 Apr 02; Vol. 12 (4), pp. e0358623. Date of Electronic Publication: 2024 Feb 23.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: ASM Press Country of Publication: United States NLM ID: 101634614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2165-0497 (Electronic) Linking ISSN: 21650497 NLM ISO Abbreviation: Microbiol Spectr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Orally available nucleoside analog UMM-766 provides protection in a murine model of orthopox disease.
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  Data: <searchLink fieldCode="AU" term="%22Mudhasani+RR%22">Mudhasani RR</searchLink>; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Golden+JW%22">Golden JW</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Adam+GC%22">Adam GC</searchLink>; Quantitative Biosciences, Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Hartingh+TJ%22">Hartingh TJ</searchLink>; Discovery Chemistry, Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Kota+KP%22">Kota KP</searchLink>; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Ordonez+D%22">Ordonez D</searchLink>; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Quackenbush+CR%22">Quackenbush CR</searchLink>; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Tran+JP%22">Tran JP</searchLink>; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Cline+C%22">Cline C</searchLink>; Pathology, Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Williams+JA%22">Williams JA</searchLink>; Pathology, Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; Pathology, Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Olsen+DB%22">Olsen DB</searchLink>; Infectious Diseases and Vaccines, Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Lieberman+LA%22">Lieberman LA</searchLink>; Discovery Immunology, Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Boyce+C%22">Boyce C</searchLink>; Discovery Pharmaceutical Sciences, Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Ginnetti+A%22">Ginnetti A</searchLink>; Discovery Chemistry, Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Meinig+JM%22">Meinig JM</searchLink>; Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Panchal+RG%22">Panchal RG</searchLink>; Molecular Biology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Mucker+EM%22">Mucker EM</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
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  Data: <searchLink fieldCode="JN" term="%22101634614%22">Microbiology spectrum</searchLink> [Microbiol Spectr] 2024 Apr 02; Vol. 12 (4), pp. e0358623. <i>Date of Electronic Publication: </i>2024 Feb 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22ASM+Press%22">ASM Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101634614 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2165-0497 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221650497%22">21650497 </searchLink><i>NLM ISO Abbreviation: </i>Microbiol Spectr <i>Subsets: </i>MEDLINE
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              Text: 2024 Apr 02
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