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An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients.

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Title: An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients.
Authors: Debing Y; Aligos Belgium BV, Leuven, Belgium. Electronic address: ydebing@aligos.com., Vanrusselt H; Aligos Belgium BV, Leuven, Belgium., Degrauwe L; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium., Silva de Oliveira DA; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium., Kariuki CK; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium., Ebwanga EJ; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium., Bashir S; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium., Merckx W; TRANSfarm, Science, Engineering & Technology Group, KU Leuven, Leuven, Belgium., Thatikonda SK; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Rajwanshi V; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Gohil V; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Hong J; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Kum DB; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Acosta Sanchez A; Novalix, Braine-l'Alleud, Belgium., Chanda S; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Blatt LM; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Jekle A; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Symons JA; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Smith DB; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Raboisson P; Aligos Belgium BV, Leuven, Belgium., Lin TI; Aligos Belgium BV, Leuven, Belgium., Beigelman L; Aligos Therapeutics, Inc., South San Francisco, CA, USA., Paeshuyse J; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium. Electronic address: jan.paeshuyse@kuleuven.be.
Source: Antiviral research [Antiviral Res] 2024 Apr; Vol. 224, pp. 105835. Date of Electronic Publication: 2024 Feb 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients.
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  Data: <searchLink fieldCode="AU" term="%22Debing+Y%22">Debing Y</searchLink>; Aligos Belgium BV, Leuven, Belgium. Electronic address: ydebing@aligos.com.<br /><searchLink fieldCode="AU" term="%22Vanrusselt+H%22">Vanrusselt H</searchLink>; Aligos Belgium BV, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Degrauwe+L%22">Degrauwe L</searchLink>; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Silva+de+Oliveira+DA%22">Silva de Oliveira DA</searchLink>; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Kariuki+CK%22">Kariuki CK</searchLink>; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Ebwanga+EJ%22">Ebwanga EJ</searchLink>; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Bashir+S%22">Bashir S</searchLink>; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Merckx+W%22">Merckx W</searchLink>; TRANSfarm, Science, Engineering & Technology Group, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Thatikonda+SK%22">Thatikonda SK</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rajwanshi+V%22">Rajwanshi V</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gohil+V%22">Gohil V</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hong+J%22">Hong J</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kum+DB%22">Kum DB</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Acosta+Sanchez+A%22">Acosta Sanchez A</searchLink>; Novalix, Braine-l'Alleud, Belgium.<br /><searchLink fieldCode="AU" term="%22Chanda+S%22">Chanda S</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Blatt+LM%22">Blatt LM</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jekle+A%22">Jekle A</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Symons+JA%22">Symons JA</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Smith+DB%22">Smith DB</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Raboisson+P%22">Raboisson P</searchLink>; Aligos Belgium BV, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Lin+TI%22">Lin TI</searchLink>; Aligos Belgium BV, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Beigelman+L%22">Beigelman L</searchLink>; Aligos Therapeutics, Inc., South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Paeshuyse+J%22">Paeshuyse J</searchLink>; Laboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, Leuven, Belgium. Electronic address: jan.paeshuyse@kuleuven.be.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8109699 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-9096 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201663542%22">01663542 </searchLink><i>NLM ISO Abbreviation: </i>Antiviral Res <i>Subsets: </i>MEDLINE
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