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Combined in vitro and in silico mechanistic approach to explore the potential of Alternaria mycotoxins alternariol and altertoxin II to hamper γH2AX formation in DNA damage signaling pathways.

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Title: Combined in vitro and in silico mechanistic approach to explore the potential of Alternaria mycotoxins alternariol and altertoxin II to hamper γH2AX formation in DNA damage signaling pathways.
Authors: Crudo F; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria., Dellafiora L; Department of Food and Drug, University of Parma, Area Parco delle Scienze 27/A, Parma 43124, Italy., Hong C; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria., Burger L; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria., Jobst M; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währinger Str. 42, Vienna 1090, Austria; University of Vienna, Vienna Doctoral School in Chemistry (DoSChem), Währinger Str. 42, Vienna 1090, Austria., Del Favero G; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währinger Str. 42, Vienna 1090, Austria., Marko D; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währinger Str. 42, Vienna 1090, Austria. Electronic address: doris.marko@univie.ac.at.
Source: Toxicology letters [Toxicol Lett] 2024 Apr; Vol. 394, pp. 1-10. Date of Electronic Publication: 2024 Feb 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol Lett Subsets: MEDLINE
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  Data: Combined in vitro and in silico mechanistic approach to explore the potential of Alternaria mycotoxins alternariol and altertoxin II to hamper γH2AX formation in DNA damage signaling pathways.
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  Data: <searchLink fieldCode="AU" term="%22Crudo+F%22">Crudo F</searchLink>; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Dellafiora+L%22">Dellafiora L</searchLink>; Department of Food and Drug, University of Parma, Area Parco delle Scienze 27/A, Parma 43124, Italy.<br /><searchLink fieldCode="AU" term="%22Hong+C%22">Hong C</searchLink>; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Burger+L%22">Burger L</searchLink>; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Jobst+M%22">Jobst M</searchLink>; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währinger Str. 42, Vienna 1090, Austria; University of Vienna, Vienna Doctoral School in Chemistry (DoSChem), Währinger Str. 42, Vienna 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Del+Favero+G%22">Del Favero G</searchLink>; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währinger Str. 42, Vienna 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Marko+D%22">Marko D</searchLink>; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Währinger Str. 38, Vienna 1090, Austria; Core Facility Multimodal Imaging, Faculty of Chemistry, University of Vienna, Währinger Str. 42, Vienna 1090, Austria. Electronic address: doris.marko@univie.ac.at.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7709027 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-3169 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203784274%22">03784274 </searchLink><i>NLM ISO Abbreviation: </i>Toxicol Lett <i>Subsets: </i>MEDLINE
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