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Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy.

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Title: Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy.
Authors: Toral-Rios D; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA., Long JM; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine , St Louis, MO, USA., Ulrich JD; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA., Yu J; Department of Genetics, Genome Technology Access Center at the McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA., Strickland MR; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA., Han X; Department of Medicine, Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio, San Antonio, TX, USA., Holtzman DM; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine , St Louis, MO, USA., Cashikar AG; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine , St Louis, MO, USA., Paul SM; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine , St Louis, MO, USA.
Source: The Journal of experimental medicine [J Exp Med] 2024 Apr 01; Vol. 221 (4). Date of Electronic Publication: 2024 Mar 01.
Publication Type: Journal Article
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
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  Data: Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy.
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  Data: <searchLink fieldCode="AU" term="%22Toral-Rios+D%22">Toral-Rios D</searchLink>; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Long+JM%22">Long JM</searchLink>; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine , St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Ulrich+JD%22">Ulrich JD</searchLink>; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Department of Genetics, Genome Technology Access Center at the McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Strickland+MR%22">Strickland MR</searchLink>; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Han+X%22">Han X</searchLink>; Department of Medicine, Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine , St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Cashikar+AG%22">Cashikar AG</searchLink>; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine , St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Paul+SM%22">Paul SM</searchLink>; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine , St Louis, MO, USA.; Taylor Family Institute for Innovative Psychiatric Research, Washington University School of Medicine , St Louis, MO, USA.
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  Data: <searchLink fieldCode="JN" term="%222985109R%22">The Journal of experimental medicine</searchLink> [J Exp Med] 2024 Apr 01; Vol. 221 (4). <i>Date of Electronic Publication: </i>2024 Mar 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Rockefeller+University+Press%22">Rockefeller University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985109R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1540-9538 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221007%22">00221007 </searchLink><i>NLM ISO Abbreviation: </i>J Exp Med <i>Subsets: </i>MEDLINE
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        Value: 10.1084/jem.20232000
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              Text: 2024 Apr 01
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