Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing-remitting multiple sclerosis, the ProVal-MS study.

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Title: Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing-remitting multiple sclerosis, the ProVal-MS study.
Authors: Bayas A; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany. antonios.bayas@uk-augsburg.de., Mansmann U; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany., Ön BI; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany., Hoffmann VS; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany., Berthele A; Department of Neurology, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany., Mühlau M; Department of Neurology, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany., Kowarik MC; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany., Krumbholz M; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany., Senel M; Department of Neurology, University Hospital Ulm, Ulm, Germany., Steuerwald V; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany., Naumann M; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany., Hartberger J; Department of Neurology, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany., Kerschensteiner M; Institute of Clinical Neuroimmunology, LMU Hospital, Ludwig-Maximilians-Universität München, Munich, Germany., Oswald E; Institute of Clinical Neuroimmunology, LMU Hospital, Ludwig-Maximilians-Universität München, Munich, Germany., Ruschil C; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany., Ziemann U; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany., Tumani H; Department of Neurology, University Hospital Ulm, Ulm, Germany., Vardakas I; Department of Neurology, University Hospital Ulm, Ulm, Germany., Albashiti F; Medical Data Integration Center, University Hospital, LMU Munich, Munich, Germany., Kramer F; IT-Infrastructure for Translational Medical Research, University of Augsburg, Augsburg, Germany., Soto-Rey I; Medical Data Integration Center, Institute of Digital Medicine, University Hospital Augsburg, Augsburg, Germany., Spengler H; Medical Data Integration Center, Medical Center rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany., Mayer G; Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany., Kestler HA; Institute of Medical Systems Biology, Ulm University, Ulm, Germany., Kohlbacher O; Institute for Translational Bioinformatics, University Hospital Tübingen, Tübingen, Germany.; Department of Computer Science, University of Tübingen, Tübingen, Germany.; Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany., Hagedorn M; Medical Data Integration Center, University Hospital, LMU Munich, Munich, Germany., Boeker M; Institute for Artificial Intelligence and Informatics in Medicine, Medical Center rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany., Kuhn K; Institute for Artificial Intelligence and Informatics in Medicine, Medical Center rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany., Buchka S; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany., Kohlmayer F; Bitcare GmbH, Munich, Germany., Kirschke JS; Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Behrens L; Diagnostic and Interventional Neuroradiology, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Zimmermann H; Institute of Neuroradiology, LMU Hospital, Ludwig-Maximilians-Universität München, Munich, Germany., Bender B; Department of Diagnostic and Interventional Neuroradiology, University Hospital Tübingen, Tübingen, Germany., Sollmann N; Department of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany., Havla J; Institute of Clinical Neuroimmunology, LMU Hospital, Ludwig-Maximilians-Universität München, Munich, Germany., Hemmer B; Department of Neurology, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Corporate Authors: ProVal-MS study group
Source: Neurological research and practice [Neurol Res Pract] 2024 Mar 07; Vol. 6 (1), pp. 15. Date of Electronic Publication: 2024 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: BMC Country of Publication: England NLM ID: 101767802 Publication Model: Electronic Cited Medium: Internet ISSN: 2524-3489 (Electronic) Linking ISSN: 25243489 NLM ISO Abbreviation: Neurol Res Pract Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing-remitting multiple sclerosis, the ProVal-MS study.
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  Data: <searchLink fieldCode="AU" term="%22Bayas+A%22">Bayas A</searchLink>; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany. antonios.bayas@uk-augsburg.de.<br /><searchLink fieldCode="AU" term="%22Mansmann+U%22">Mansmann U</searchLink>; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ön+BI%22">Ön BI</searchLink>; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+VS%22">Hoffmann VS</searchLink>; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Berthele+A%22">Berthele A</searchLink>; Department of Neurology, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mühlau+M%22">Mühlau M</searchLink>; Department of Neurology, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kowarik+MC%22">Kowarik MC</searchLink>; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Krumbholz+M%22">Krumbholz M</searchLink>; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Senel+M%22">Senel M</searchLink>; Department of Neurology, University Hospital Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Steuerwald+V%22">Steuerwald V</searchLink>; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Naumann+M%22">Naumann M</searchLink>; Department of Neurology and Clinical Neurophysiology, Medical Faculty, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hartberger+J%22">Hartberger J</searchLink>; Department of Neurology, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kerschensteiner+M%22">Kerschensteiner M</searchLink>; Institute of Clinical Neuroimmunology, LMU Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Oswald+E%22">Oswald E</searchLink>; Institute of Clinical Neuroimmunology, LMU Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ruschil+C%22">Ruschil C</searchLink>; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ziemann+U%22">Ziemann U</searchLink>; Department of Neurology and Stroke, and Hertie-Institute for Clinical Brain Research, Eberhard-Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Tumani+H%22">Tumani H</searchLink>; Department of Neurology, University Hospital Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Vardakas+I%22">Vardakas I</searchLink>; Department of Neurology, University Hospital Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Albashiti+F%22">Albashiti F</searchLink>; Medical Data Integration Center, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kramer+F%22">Kramer F</searchLink>; IT-Infrastructure for Translational Medical Research, University of Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Soto-Rey+I%22">Soto-Rey I</searchLink>; Medical Data Integration Center, Institute of Digital Medicine, University Hospital Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Spengler+H%22">Spengler H</searchLink>; Medical Data Integration Center, Medical Center rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mayer+G%22">Mayer G</searchLink>; Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kestler+HA%22">Kestler HA</searchLink>; Institute of Medical Systems Biology, Ulm University, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Kohlbacher+O%22">Kohlbacher O</searchLink>; Institute for Translational Bioinformatics, University Hospital Tübingen, Tübingen, Germany.; Department of Computer Science, University of Tübingen, Tübingen, Germany.; Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hagedorn+M%22">Hagedorn M</searchLink>; Medical Data Integration Center, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Boeker+M%22">Boeker M</searchLink>; Institute for Artificial Intelligence and Informatics in Medicine, Medical Center rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kuhn+K%22">Kuhn K</searchLink>; Institute for Artificial Intelligence and Informatics in Medicine, Medical Center rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Buchka+S%22">Buchka S</searchLink>; Institute of Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kohlmayer+F%22">Kohlmayer F</searchLink>; Bitcare GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kirschke+JS%22">Kirschke JS</searchLink>; Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Behrens+L%22">Behrens L</searchLink>; 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Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
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