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Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study.

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Title: Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study.
Authors: Kay A; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini. Electronic address: Alexander.Kay@bcm.edu., Vasiliu A; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Carratala-Castro L; Barcelona Institute for Global Health, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique., Mtafya B; National Institute for Medical Research (NIMR)-Mbeya Medical Research Center, Mbeya, Tanzania., Mendez Reyes JE; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Maphalala N; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini., Munguambe S; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique., Mulengwa D; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini., Ness T; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Saavedra B; Barcelona Institute for Global Health, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique., Bacha J; Baylor College of Medicine Children's Foundation Mbeya, Mbeya, Tanzania., Maphalala G; Eswatini Health Laboratory Service, Mbabane, Eswatini., Mejia R; Pediatric Tropical Medicine, Baylor College of Medicine, Houston, TX, USA., Mtetwa G; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Acacio S; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique., Manjate P; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique., Mambuque E; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique., Shiba N; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini., Kota N; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini., Ziyane M; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini; Eswatini Health Laboratory Service, Mbabane, Eswatini., Ntinginya NE; National Institute for Medical Research (NIMR)-Mbeya Medical Research Center, Mbeya, Tanzania., Lange C; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Respiratory Medicine and International Health, University of Lübeck, Lübeck, Germany., Kirchner HL; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Population Health Sciences, Geisinger, Danville, PA, USA., DiNardo AR; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands., Garcia-Basteiro AL; Barcelona Institute for Global Health, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain., Mandalakas AM; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health School of Public Health, Houston, TX, USA.
Corporate Authors: Stool4TB Global Partnership
Source: The Lancet. Microbe [Lancet Microbe] 2024 May; Vol. 5 (5), pp. e433-e441. Date of Electronic Publication: 2024 Mar 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Multicenter Study; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101769019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-5247 (Electronic) Linking ISSN: 26665247 NLM ISO Abbreviation: Lancet Microbe Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study.
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  Data: <searchLink fieldCode="AU" term="%22Kay+A%22">Kay A</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini. Electronic address: Alexander.Kay@bcm.edu.<br /><searchLink fieldCode="AU" term="%22Vasiliu+A%22">Vasiliu A</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Carratala-Castro+L%22">Carratala-Castro L</searchLink>; Barcelona Institute for Global Health, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Mtafya+B%22">Mtafya B</searchLink>; National Institute for Medical Research (NIMR)-Mbeya Medical Research Center, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Mendez+Reyes+JE%22">Mendez Reyes JE</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Maphalala+N%22">Maphalala N</searchLink>; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini.<br /><searchLink fieldCode="AU" term="%22Munguambe+S%22">Munguambe S</searchLink>; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Mulengwa+D%22">Mulengwa D</searchLink>; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini.<br /><searchLink fieldCode="AU" term="%22Ness+T%22">Ness T</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Saavedra+B%22">Saavedra B</searchLink>; Barcelona Institute for Global Health, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Bacha+J%22">Bacha J</searchLink>; Baylor College of Medicine Children's Foundation Mbeya, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Maphalala+G%22">Maphalala G</searchLink>; Eswatini Health Laboratory Service, Mbabane, Eswatini.<br /><searchLink fieldCode="AU" term="%22Mejia+R%22">Mejia R</searchLink>; Pediatric Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Mtetwa+G%22">Mtetwa G</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Acacio+S%22">Acacio S</searchLink>; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Manjate+P%22">Manjate P</searchLink>; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Mambuque+E%22">Mambuque E</searchLink>; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique.<br /><searchLink fieldCode="AU" term="%22Shiba+N%22">Shiba N</searchLink>; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini.<br /><searchLink fieldCode="AU" term="%22Kota+N%22">Kota N</searchLink>; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini.<br /><searchLink fieldCode="AU" term="%22Ziyane+M%22">Ziyane M</searchLink>; Baylor College of Medicine Children's Foundation Eswatini, Mbabane, Eswatini; Eswatini Health Laboratory Service, Mbabane, Eswatini.<br /><searchLink fieldCode="AU" term="%22Ntinginya+NE%22">Ntinginya NE</searchLink>; National Institute for Medical Research (NIMR)-Mbeya Medical Research Center, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Lange+C%22">Lange C</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Respiratory Medicine and International Health, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Kirchner+HL%22">Kirchner HL</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Population Health Sciences, Geisinger, Danville, PA, USA.<br /><searchLink fieldCode="AU" term="%22DiNardo+AR%22">DiNardo AR</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Garcia-Basteiro+AL%22">Garcia-Basteiro AL</searchLink>; Barcelona Institute for Global Health, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; Centro de Investigação em Saude de Manhiça (CISM), Maputo, Mozambique; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mandalakas+AM%22">Mandalakas AM</searchLink>; Global TB Program, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany; Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health School of Public Health, Houston, TX, USA.
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  Data: <searchLink fieldCode="JN" term="%22101769019%22">The Lancet. Microbe</searchLink> [Lancet Microbe] 2024 May; Vol. 5 (5), pp. e433-e441. <i>Date of Electronic Publication: </i>2024 Mar 07.
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