Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS.

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Title: Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS.
Authors: Hilton JBW; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Kysenius K; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Liddell JR; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Mercer SW; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia., Paul B; School of Geography, Earth and Atmospheric Sciences, The University of Melbourne, Victoria, 3010, Australia.; Elemental Scientific Lasers, LLC, 685 Old Buffalo Trail, Bozeman, MT, 59715, USA., Beckman JS; Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, 97331, USA., McLean CA; Department of Anatomical Pathology, The Alfred Hospital, Victoria, 3004, Australia., White AR; Mental Health Program, Department of Cell and Molecular Biology, Queensland Institute of Biomedical Research Berghofer, Herston, QLD, 4006, Australia., Donnelly PS; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, 3010, Australia., Bush AI; Melbourne Dementia Research Centre, The University of Melbourne and Florey Institute of Neuroscience and Mental Health, Victoria, 3010, Australia., Hare DJ; Atomic Medicine Initiative, University of Technology Sydney, Ultimo, NSW, 2007, Australia., Roberts BR; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA., Crouch PJ; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia. pjcrouch@unimelb.edu.au.
Source: Scientific reports [Sci Rep] 2024 Mar 11; Vol. 14 (1), pp. 5929. Date of Electronic Publication: 2024 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Evidence for disrupted copper availability in human spinal cord supports Cu<superscript>II</superscript>(atsm) as a treatment option for sporadic cases of ALS.
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  Data: <searchLink fieldCode="AU" term="%22Hilton+JBW%22">Hilton JBW</searchLink>; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Kysenius+K%22">Kysenius K</searchLink>; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Liddell+JR%22">Liddell JR</searchLink>; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Mercer+SW%22">Mercer SW</searchLink>; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Paul+B%22">Paul B</searchLink>; School of Geography, Earth and Atmospheric Sciences, The University of Melbourne, Victoria, 3010, Australia.; Elemental Scientific Lasers, LLC, 685 Old Buffalo Trail, Bozeman, MT, 59715, USA.<br /><searchLink fieldCode="AU" term="%22Beckman+JS%22">Beckman JS</searchLink>; Linus Pauling Institute and Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, 97331, USA.<br /><searchLink fieldCode="AU" term="%22McLean+CA%22">McLean CA</searchLink>; Department of Anatomical Pathology, The Alfred Hospital, Victoria, 3004, Australia.<br /><searchLink fieldCode="AU" term="%22White+AR%22">White AR</searchLink>; Mental Health Program, Department of Cell and Molecular Biology, Queensland Institute of Biomedical Research Berghofer, Herston, QLD, 4006, Australia.<br /><searchLink fieldCode="AU" term="%22Donnelly+PS%22">Donnelly PS</searchLink>; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Bush+AI%22">Bush AI</searchLink>; Melbourne Dementia Research Centre, The University of Melbourne and Florey Institute of Neuroscience and Mental Health, Victoria, 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Hare+DJ%22">Hare DJ</searchLink>; Atomic Medicine Initiative, University of Technology Sydney, Ultimo, NSW, 2007, Australia.<br /><searchLink fieldCode="AU" term="%22Roberts+BR%22">Roberts BR</searchLink>; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, 30322, USA.<br /><searchLink fieldCode="AU" term="%22Crouch+PJ%22">Crouch PJ</searchLink>; Department of Anatomy and Physiology, The University of Melbourne, Victoria, 3010, Australia. pjcrouch@unimelb.edu.au.
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