A solid beta-sheet structure is formed at the surface of FUS droplets during aging.

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Title: A solid beta-sheet structure is formed at the surface of FUS droplets during aging.
Authors: Emmanouilidis L; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland. leonidas@bc.biol.ethz.ch.; Bringing Materials to Life Initiative, ETH Zurich, Zurich, Switzerland. leonidas@bc.biol.ethz.ch., Bartalucci E; Max Planck Institute for Chemical Energy Conversion, Mülheim/Ruhr, Germany.; Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Aachen, Germany., Kan Y; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.; Max Planck Institute for Polymer Research, Mainz, Germany., Ijavi M; Department of Materials, ETH Zurich, Zurich, Switzerland., Pérez ME; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland., Afanasyev P; Cryo-EM Knowledge Hub, ETH Zurich, Zurich, Switzerland., Boehringer D; Cryo-EM Knowledge Hub, ETH Zurich, Zurich, Switzerland., Zehnder J; Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland., Parekh SH; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.; Max Planck Institute for Polymer Research, Mainz, Germany., Bonn M; Max Planck Institute for Polymer Research, Mainz, Germany., Michaels TCT; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.; Bringing Materials to Life Initiative, ETH Zurich, Zurich, Switzerland., Wiegand T; Max Planck Institute for Chemical Energy Conversion, Mülheim/Ruhr, Germany. thomas.wiegand@cec.mpg.de.; Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Aachen, Germany. thomas.wiegand@cec.mpg.de.; Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland. thomas.wiegand@cec.mpg.de., Allain FH; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland. allain@bc.biol.ethz.ch.; Bringing Materials to Life Initiative, ETH Zurich, Zurich, Switzerland. allain@bc.biol.ethz.ch.
Source: Nature chemical biology [Nat Chem Biol] 2024 Aug; Vol. 20 (8), pp. 1044-1052. Date of Electronic Publication: 2024 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Emmanouilidis+L%22">Emmanouilidis L</searchLink>; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland. leonidas@bc.biol.ethz.ch.; Bringing Materials to Life Initiative, ETH Zurich, Zurich, Switzerland. leonidas@bc.biol.ethz.ch.<br /><searchLink fieldCode="AU" term="%22Bartalucci+E%22">Bartalucci E</searchLink>; Max Planck Institute for Chemical Energy Conversion, Mülheim/Ruhr, Germany.; Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Kan+Y%22">Kan Y</searchLink>; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.; Max Planck Institute for Polymer Research, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Ijavi+M%22">Ijavi M</searchLink>; Department of Materials, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pérez+ME%22">Pérez ME</searchLink>; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Afanasyev+P%22">Afanasyev P</searchLink>; Cryo-EM Knowledge Hub, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Boehringer+D%22">Boehringer D</searchLink>; Cryo-EM Knowledge Hub, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zehnder+J%22">Zehnder J</searchLink>; Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Parekh+SH%22">Parekh SH</searchLink>; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.; Max Planck Institute for Polymer Research, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Bonn+M%22">Bonn M</searchLink>; Max Planck Institute for Polymer Research, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Michaels+TCT%22">Michaels TCT</searchLink>; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.; Bringing Materials to Life Initiative, ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wiegand+T%22">Wiegand T</searchLink>; Max Planck Institute for Chemical Energy Conversion, Mülheim/Ruhr, Germany. thomas.wiegand@cec.mpg.de.; Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Aachen, Germany. thomas.wiegand@cec.mpg.de.; Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland. thomas.wiegand@cec.mpg.de.<br /><searchLink fieldCode="AU" term="%22Allain+FH%22">Allain FH</searchLink>; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland. allain@bc.biol.ethz.ch.; Bringing Materials to Life Initiative, ETH Zurich, Zurich, Switzerland. allain@bc.biol.ethz.ch.
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