Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays.
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| Title: | Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays. |
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| Authors: | van Veggel L; Department of Neuroscience, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, 3590 Hasselt, Belgium.; Department of Psychiatry and Neuropsychology, Division of Translational Neuroscience, European Graduate School of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, 6200 Maastricht, The Netherlands.; University MS Center (UMSC), 3900 Hasselt-Pelt, Belgium., Mocking TAM; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Sijben HJ; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Liu R; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Gorostiola González M; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Dilweg MA; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Royakkers J; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 Maastricht, The Netherlands., Li A; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Kumar V; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Dong YY; Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, OX3 7BN Oxford, U.K., Bullock A; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Sauer DB; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, U.K., Diliën H; Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 Maastricht, The Netherlands., van Westen GJP; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands., Schreiber R; Section of Psychopharmacology, Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, 6200 Maastricht, The Netherlands., Heitman LH; Leiden Academic Centre for Drug Research (LACDR), Division of Drug Discovery and Safety, Leiden University, 2333 Leiden, The Netherlands.; Oncode Institute, Einsteinweg 55, 2333 Leiden, The Netherlands., Vanmierlo T; Department of Neuroscience, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, 3590 Hasselt, Belgium.; Department of Psychiatry and Neuropsychology, Division of Translational Neuroscience, European Graduate School of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, 6200 Maastricht, The Netherlands.; University MS Center (UMSC), 3900 Hasselt-Pelt, Belgium. |
| Source: | ACS chemical neuroscience [ACS Chem Neurosci] 2024 Apr 03; Vol. 15 (7), pp. 1424-1431. Date of Electronic Publication: 2024 Mar 13. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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