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Blocking the CTLA-4 and PD-1 pathways during pulmonary paracoccidioidomycosis improves immunity, reduces disease severity, and increases the survival of infected mice.

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Title: Blocking the CTLA-4 and PD-1 pathways during pulmonary paracoccidioidomycosis improves immunity, reduces disease severity, and increases the survival of infected mice.
Authors: Preite NW; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil., Borges BM; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil., Kaminski VL; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil., Ayupe MC; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Gonçalves LM; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Dos Santos BV; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil., Fonseca DLM; Institute of Mathematics and Statistics (IME), University of Sao Paulo (USP), Sao Paulo, Brazil., Filgueiras IS; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Salgado CL; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Muxel SM; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Cabral-Marques O; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.; Department of Medicine, Division of Molecular Medicine, University of São Paulo School of Medicine (USP), São Paulo, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil.; Network of Immunity in Infection, Malignancy, Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), São Paulo, Brazil., da Fonseca DM; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Loures FV; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil., Calich VLG; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Source: Frontiers in immunology [Front Immunol] 2024 Mar 04; Vol. 15, pp. 1347318. Date of Electronic Publication: 2024 Mar 04 (Print Publication: 2024).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Blocking the CTLA-4 and PD-1 pathways during pulmonary paracoccidioidomycosis improves immunity, reduces disease severity, and increases the survival of infected mice.
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  Data: <searchLink fieldCode="AU" term="%22Preite+NW%22">Preite NW</searchLink>; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Borges+BM%22">Borges BM</searchLink>; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Kaminski+VL%22">Kaminski VL</searchLink>; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Ayupe+MC%22">Ayupe MC</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Gonçalves+LM%22">Gonçalves LM</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+BV%22">Dos Santos BV</searchLink>; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Fonseca+DLM%22">Fonseca DLM</searchLink>; Institute of Mathematics and Statistics (IME), University of Sao Paulo (USP), Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Filgueiras+IS%22">Filgueiras IS</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Salgado+CL%22">Salgado CL</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Muxel+SM%22">Muxel SM</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Cabral-Marques+O%22">Cabral-Marques O</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.; Department of Medicine, Division of Molecular Medicine, University of São Paulo School of Medicine (USP), São Paulo, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil.; Network of Immunity in Infection, Malignancy, Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Fonseca+DM%22">da Fonseca DM</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Loures+FV%22">Loures FV</searchLink>; Institute of Science and Technology, Federal University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Calich+VLG%22">Calich VLG</searchLink>; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.
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