View in EDS

Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing.

Saved in:
Bibliographic Details
Title: Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing.
Authors: Appelbaum J; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.; Division of Hematology/Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.; Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Seattle Children's Hospital, Seattle, Washington, USA., Price AE; 2seventy bio, Cambridge, Massachusetts, USA., Oda K; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Zhang J; 2seventy bio, Cambridge, Massachusetts, USA., Leung WH; 2seventy bio, Cambridge, Massachusetts, USA., Tampella G; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Xia D; 2seventy bio, Cambridge, Massachusetts, USA., So PP; 2seventy bio, Cambridge, Massachusetts, USA., Hilton SK; 2seventy bio, Cambridge, Massachusetts, USA., Evandy C; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Sarkar S; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Martin U; 2seventy bio, Cambridge, Massachusetts, USA., Krostag AR; 2seventy bio, Cambridge, Massachusetts, USA., Leonardi M; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Zak DE; 2seventy bio, Cambridge, Massachusetts, USA., Logan R; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Lewis P; 2seventy bio, Cambridge, Massachusetts, USA., Franke-Welch S; 2seventy bio, Cambridge, Massachusetts, USA., Ngwenyama N; 2seventy bio, Cambridge, Massachusetts, USA., Fitzgerald M; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Tulberg N; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Rawlings-Rhea S; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Gardner RA; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Jones K; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Sanabria A; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Crago W; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Timmer J; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Hollands A; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Eckelman B; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA., Bilic S; Vandro Consulting, Waukee, Iowa, USA., Woodworth J; Vandro Consulting, Waukee, Iowa, USA., Lamble A; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.; Seattle Children's Hospital, Seattle, Washington, USA., Gregory PD; 2seventy bio, Cambridge, Massachusetts, USA., Jarjour J; 2seventy bio, Cambridge, Massachusetts, USA., Pogson M; 2seventy bio, Cambridge, Massachusetts, USA., Gustafson JA; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA., Astrakhan A; 2seventy bio, Cambridge, Massachusetts, USA., Jensen MC; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2024 Mar 19; Vol. 134 (9). Date of Electronic Publication: 2024 Mar 19.
Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 38502193
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Appelbaum+J%22">Appelbaum J</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.; Division of Hematology/Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.; Fred Hutchinson Cancer Center, Seattle, Washington, USA.; Seattle Children's Hospital, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Price+AE%22">Price AE</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Oda+K%22">Oda K</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Leung+WH%22">Leung WH</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Tampella+G%22">Tampella G</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Xia+D%22">Xia D</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22So+PP%22">So PP</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Hilton+SK%22">Hilton SK</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Evandy+C%22">Evandy C</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Sarkar+S%22">Sarkar S</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Martin+U%22">Martin U</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Krostag+AR%22">Krostag AR</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Leonardi+M%22">Leonardi M</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Zak+DE%22">Zak DE</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Logan+R%22">Logan R</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+P%22">Lewis P</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Franke-Welch+S%22">Franke-Welch S</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ngwenyama+N%22">Ngwenyama N</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+M%22">Fitzgerald M</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Tulberg+N%22">Tulberg N</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Rawlings-Rhea+S%22">Rawlings-Rhea S</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Gardner+RA%22">Gardner RA</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Jones+K%22">Jones K</searchLink>; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Sanabria+A%22">Sanabria A</searchLink>; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Crago+W%22">Crago W</searchLink>; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Timmer+J%22">Timmer J</searchLink>; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Hollands+A%22">Hollands A</searchLink>; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Eckelman+B%22">Eckelman B</searchLink>; Inhibrx, Torrey Pines Science Park, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Bilic+S%22">Bilic S</searchLink>; Vandro Consulting, Waukee, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Woodworth+J%22">Woodworth J</searchLink>; Vandro Consulting, Waukee, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Lamble+A%22">Lamble A</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.; Seattle Children's Hospital, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Gregory+PD%22">Gregory PD</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Jarjour+J%22">Jarjour J</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Pogson+M%22">Pogson M</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Gustafson+JA%22">Gustafson JA</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Astrakhan+A%22">Astrakhan A</searchLink>; 2seventy bio, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Jensen+MC%22">Jensen MC</searchLink>; Seattle Children's Therapeutics, Seattle Children's Research Institute, Seattle, Washington, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2024 Mar 19; Vol. 134 (9). <i>Date of Electronic Publication: </i>2024 Mar 19.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38502193
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1172/JCI162593
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Drug-regulated CD33-targeted CAR T cells control AML using clinically optimized rapamycin dosing.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Appelbaum J
      – PersonEntity:
          Name:
            NameFull: Price AE
      – PersonEntity:
          Name:
            NameFull: Oda K
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Leung WH
      – PersonEntity:
          Name:
            NameFull: Tampella G
      – PersonEntity:
          Name:
            NameFull: Xia D
      – PersonEntity:
          Name:
            NameFull: So PP
      – PersonEntity:
          Name:
            NameFull: Hilton SK
      – PersonEntity:
          Name:
            NameFull: Evandy C
      – PersonEntity:
          Name:
            NameFull: Sarkar S
      – PersonEntity:
          Name:
            NameFull: Martin U
      – PersonEntity:
          Name:
            NameFull: Krostag AR
      – PersonEntity:
          Name:
            NameFull: Leonardi M
      – PersonEntity:
          Name:
            NameFull: Zak DE
      – PersonEntity:
          Name:
            NameFull: Logan R
      – PersonEntity:
          Name:
            NameFull: Lewis P
      – PersonEntity:
          Name:
            NameFull: Franke-Welch S
      – PersonEntity:
          Name:
            NameFull: Ngwenyama N
      – PersonEntity:
          Name:
            NameFull: Fitzgerald M
      – PersonEntity:
          Name:
            NameFull: Tulberg N
      – PersonEntity:
          Name:
            NameFull: Rawlings-Rhea S
      – PersonEntity:
          Name:
            NameFull: Gardner RA
      – PersonEntity:
          Name:
            NameFull: Jones K
      – PersonEntity:
          Name:
            NameFull: Sanabria A
      – PersonEntity:
          Name:
            NameFull: Crago W
      – PersonEntity:
          Name:
            NameFull: Timmer J
      – PersonEntity:
          Name:
            NameFull: Hollands A
      – PersonEntity:
          Name:
            NameFull: Eckelman B
      – PersonEntity:
          Name:
            NameFull: Bilic S
      – PersonEntity:
          Name:
            NameFull: Woodworth J
      – PersonEntity:
          Name:
            NameFull: Lamble A
      – PersonEntity:
          Name:
            NameFull: Gregory PD
      – PersonEntity:
          Name:
            NameFull: Jarjour J
      – PersonEntity:
          Name:
            NameFull: Pogson M
      – PersonEntity:
          Name:
            NameFull: Gustafson JA
      – PersonEntity:
          Name:
            NameFull: Astrakhan A
      – PersonEntity:
          Name:
            NameFull: Jensen MC
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 19
              M: 03
              Text: 2024 Mar 19
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 1558-8238
          Numbering:
            – Type: volume
              Value: 134
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: The Journal of clinical investigation
              Type: main
ResultId 1