The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease.

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Title: The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease.
Authors: Bishop RT; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Miller AK; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Froid M; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA., Nerlakanti N; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA., Li T; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Frieling JS; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Nasr MM; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA., Nyman KJ; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA., Sudalagunta PR; Department of Metabolism and Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Canevarolo RR; Department of Metabolism and Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Silva AS; Department of Metabolism and Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Shain KH; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA., Lynch CC; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. conor.lynch@moffitt.org., Basanta D; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. david@cancerevo.org.
Source: Nature communications [Nat Commun] 2024 Mar 19; Vol. 15 (1), pp. 2458. Date of Electronic Publication: 2024 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: The bone ecosystem facilitates multiple myeloma relapse and the evolution of heterogeneous drug resistant disease.
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  Data: <searchLink fieldCode="AU" term="%22Bishop+RT%22">Bishop RT</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Miller+AK%22">Miller AK</searchLink>; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Froid+M%22">Froid M</searchLink>; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Nerlakanti+N%22">Nerlakanti N</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Frieling+JS%22">Frieling JS</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Nasr+MM%22">Nasr MM</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Nyman+KJ%22">Nyman KJ</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; The Cancer Biology Ph.D. Program, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sudalagunta+PR%22">Sudalagunta PR</searchLink>; Department of Metabolism and Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Canevarolo+RR%22">Canevarolo RR</searchLink>; Department of Metabolism and Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Silva+AS%22">Silva AS</searchLink>; Department of Metabolism and Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Shain+KH%22">Shain KH</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.; Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.<br /><searchLink fieldCode="AU" term="%22Lynch+CC%22">Lynch CC</searchLink>; Department of Tumor Microenvironment and Metastasis, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. conor.lynch@moffitt.org.<br /><searchLink fieldCode="AU" term="%22Basanta+D%22">Basanta D</searchLink>; Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. david@cancerevo.org.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Mar 19; Vol. 15 (1), pp. 2458. <i>Date of Electronic Publication: </i>2024 Mar 19.
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