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The Effect of Polymorphisms and Other Biomarkers on Infliximab Exposure in Paediatric Inflammatory Bowel Disease: Development of a Population Pharmacokinetic Model.

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Title: The Effect of Polymorphisms and Other Biomarkers on Infliximab Exposure in Paediatric Inflammatory Bowel Disease: Development of a Population Pharmacokinetic Model.
Authors: Clemente-Bautista S; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain. susana.clemente@vallhebron.cat., Trocóniz IF; Department of Pharmaceutical Technology and Chemistry, Faculty of Pharmacy and Nutrition, University of Navarra, 31009, Navarra, Spain., Segarra-Cantón Ó; Paediatric Gastroenterology and Clinical Nutrition Unit, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.; Department of Paediatrics, Obstetrics and Gynaecology, Preventive Medicine and Public Health of the Universidad Autónoma de Barcelona, 08193, Bellaterra, Spain., Salvador-Marín S; Pharmacogenetics and Pharmacogenomics Laboratory, Pharmacy Department, Gregorio Marañón University Hospital, 28007, Madrid, Spain., Parramón-Teixidó CJ; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain., Álvarez-Beltrán M; Paediatric Gastroenterology and Clinical Nutrition Unit, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain., López-Fernández LA; Pharmacogenetics and Pharmacogenomics Laboratory, Pharmacy Department, Gregorio Marañón University Hospital, 28007, Madrid, Spain., Colom H; Pharmacy and Pharmaceutical Technology and Physical Chemistry Department, University of Barcelona, 08028, Barcelona, Spain., Cabañas-Poy MJ; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain., Gorgas-Torner MQ; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain., Miarons M; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.; Pharmacy Department, Consorci Hospitalari de Vic, Vic, Barcelona, Spain.
Source: Paediatric drugs [Paediatr Drugs] 2024 May; Vol. 26 (3), pp. 331-346. Date of Electronic Publication: 2024 Mar 20.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Springer International Country of Publication: Switzerland NLM ID: 100883685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2019 (Electronic) Linking ISSN: 11745878 NLM ISO Abbreviation: Paediatr Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Clemente-Bautista+S%22">Clemente-Bautista S</searchLink>; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain. susana.clemente@vallhebron.cat.<br /><searchLink fieldCode="AU" term="%22Trocóniz+IF%22">Trocóniz IF</searchLink>; Department of Pharmaceutical Technology and Chemistry, Faculty of Pharmacy and Nutrition, University of Navarra, 31009, Navarra, Spain.<br /><searchLink fieldCode="AU" term="%22Segarra-Cantón+Ó%22">Segarra-Cantón Ó</searchLink>; Paediatric Gastroenterology and Clinical Nutrition Unit, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.; Department of Paediatrics, Obstetrics and Gynaecology, Preventive Medicine and Public Health of the Universidad Autónoma de Barcelona, 08193, Bellaterra, Spain.<br /><searchLink fieldCode="AU" term="%22Salvador-Marín+S%22">Salvador-Marín S</searchLink>; Pharmacogenetics and Pharmacogenomics Laboratory, Pharmacy Department, Gregorio Marañón University Hospital, 28007, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Parramón-Teixidó+CJ%22">Parramón-Teixidó CJ</searchLink>; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez-Beltrán+M%22">Álvarez-Beltrán M</searchLink>; Paediatric Gastroenterology and Clinical Nutrition Unit, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22López-Fernández+LA%22">López-Fernández LA</searchLink>; Pharmacogenetics and Pharmacogenomics Laboratory, Pharmacy Department, Gregorio Marañón University Hospital, 28007, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Colom+H%22">Colom H</searchLink>; Pharmacy and Pharmaceutical Technology and Physical Chemistry Department, University of Barcelona, 08028, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cabañas-Poy+MJ%22">Cabañas-Poy MJ</searchLink>; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gorgas-Torner+MQ%22">Gorgas-Torner MQ</searchLink>; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Miarons+M%22">Miarons M</searchLink>; Pharmacy Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, 08035, Barcelona, Spain.; Pharmacy Department, Consorci Hospitalari de Vic, Vic, Barcelona, Spain.
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