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The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis.

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Title: The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis.
Authors: Lenk L; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Baccelli I; OSE Immunotherapeutics, Nantes, France., Laqua A; Department of Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany., Heymann J; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Reimer C; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Dietterle A; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Winterberg D; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Mary C; OSE Immunotherapeutics, Nantes, France., Corallo F; OSE Immunotherapeutics, Nantes, France., Taurelle J; OSE Immunotherapeutics, Nantes, France., Narbeburu E; OSE Immunotherapeutics, Nantes, France., Neyton S; OSE Immunotherapeutics, Nantes, France., Déramé M; OSE Immunotherapeutics, Nantes, France., Pengam S; OSE Immunotherapeutics, Nantes, France., Vogiatzi F; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Bornhauser B; Department of Pediatric Hematology/Oncology, University Children's Hospital, Zurich, Switzerland., Bourquin JP; Department of Pediatric Hematology/Oncology, University Children's Hospital, Zurich, Switzerland., Raffel S; Department of Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany., Dovhan V; Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany., Schüler T; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany., Escherich G; Clinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., den Boer ML; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Boer JM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Wessels W; Department of Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany., Peipp M; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Alten J; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Antić Ž; Department of Human Genetics, Hannover Medical School, Hannover, Germany., Bergmann AK; Department of Human Genetics, Hannover Medical School, Hannover, Germany., Schrappe M; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Cario G; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Brüggemann M; Department of Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany., Poirier N; OSE Immunotherapeutics, Nantes, France., Schewe DM; Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Source: Blood [Blood] 2024 Jun 27; Vol. 143 (26), pp. 2735-2748.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis.
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  Data: <searchLink fieldCode="AU" term="%22Lenk+L%22">Lenk L</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Baccelli+I%22">Baccelli I</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Laqua+A%22">Laqua A</searchLink>; Department of Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Heymann+J%22">Heymann J</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Reimer+C%22">Reimer C</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Dietterle+A%22">Dietterle A</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Winterberg+D%22">Winterberg D</searchLink>; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Mary+C%22">Mary C</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Corallo+F%22">Corallo F</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Taurelle+J%22">Taurelle J</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Narbeburu+E%22">Narbeburu E</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Neyton+S%22">Neyton S</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Déramé+M%22">Déramé M</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Pengam+S%22">Pengam S</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Vogiatzi+F%22">Vogiatzi F</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Bornhauser+B%22">Bornhauser B</searchLink>; Department of Pediatric Hematology/Oncology, University Children's Hospital, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bourquin+JP%22">Bourquin JP</searchLink>; Department of Pediatric Hematology/Oncology, University Children's Hospital, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Raffel+S%22">Raffel S</searchLink>; Department of Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dovhan+V%22">Dovhan V</searchLink>; Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schüler+T%22">Schüler T</searchLink>; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Escherich+G%22">Escherich G</searchLink>; Clinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22den+Boer+ML%22">den Boer ML</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Boer+JM%22">Boer JM</searchLink>; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wessels+W%22">Wessels W</searchLink>; Department of Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Peipp+M%22">Peipp M</searchLink>; Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Alten+J%22">Alten J</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Antić+Ž%22">Antić Ž</searchLink>; Department of Human Genetics, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Bergmann+AK%22">Bergmann AK</searchLink>; Department of Human Genetics, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schrappe+M%22">Schrappe M</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Cario+G%22">Cario G</searchLink>; Department of Pediatrics I, ALL-BFM Study Group, Christian-Albrecht University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Brüggemann+M%22">Brüggemann M</searchLink>; Department of Medicine II, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Poirier+N%22">Poirier N</searchLink>; OSE Immunotherapeutics, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Schewe+DM%22">Schewe DM</searchLink>; Medical Faculty, Otto von Guericke University Magdeburg, Magdeburg, Germany.
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  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2024 Jun 27; Vol. 143 (26), pp. 2735-2748.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603509 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0020 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200064971%22">00064971 </searchLink><i>NLM ISO Abbreviation: </i>Blood <i>Subsets: </i>MEDLINE
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