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Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling.

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Title: Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling.
Authors: Chomiak AA; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Tiedemann RL; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Liu Y; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Kong X; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Cui Y; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Wiseman AK; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Thurlow KE; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA., Cornett EM; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indiana University, Indianapolis, IN 46202, USA., Topper MJ; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Baylin SB; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Rothbart SB; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.
Source: Science advances [Sci Adv] 2024 Mar 29; Vol. 10 (13), pp. eadk4423. Date of Electronic Publication: 2024 Mar 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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  Data: Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling.
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  Data: <searchLink fieldCode="AU" term="%22Chomiak+AA%22">Chomiak AA</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Tiedemann+RL%22">Tiedemann RL</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Kong+X%22">Kong X</searchLink>; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Cui+Y%22">Cui Y</searchLink>; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Wiseman+AK%22">Wiseman AK</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Thurlow+KE%22">Thurlow KE</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.<br /><searchLink fieldCode="AU" term="%22Cornett+EM%22">Cornett EM</searchLink>; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indiana University, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Topper+MJ%22">Topper MJ</searchLink>; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Baylin+SB%22">Baylin SB</searchLink>; Department of Oncology, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Rothbart+SB%22">Rothbart SB</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.
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  Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2024 Mar 29; Vol. 10 (13), pp. eadk4423. <i>Date of Electronic Publication: </i>2024 Mar 27.
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