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Gedatolisib in combination with palbociclib and endocrine therapy in women with hormone receptor-positive, HER2-negative advanced breast cancer: results from the dose expansion groups of an open-label, phase 1b study.

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Title: Gedatolisib in combination with palbociclib and endocrine therapy in women with hormone receptor-positive, HER2-negative advanced breast cancer: results from the dose expansion groups of an open-label, phase 1b study.
Authors: Layman RM; Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: rlayman@mdanderson.org., Han HS; Moffit Cancer Center, Tampa, FL, USA., Rugo HS; Division of Hematology and Oncology, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA, USA., Stringer-Reasor EM; Division of Hematology Oncology, Department of Medicine, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Specht JM; Division of Hematology and Oncology, Fred Hutch Cancer Center, University of Washington, Seattle, WA, USA., Dees EC; Division of Oncology, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA., Kabos P; Division of Medical Oncology, University of Colorado Hospital, Aurora, CO, USA., Suzuki S; Celcuity, Minneapolis, MN, USA., Mutka SC; Celcuity, Minneapolis, MN, USA., Sullivan BF; Celcuity, Minneapolis, MN, USA., Gorbatchevsky I; Celcuity, Minneapolis, MN, USA., Wesolowski R; Department. of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Source: The Lancet. Oncology [Lancet Oncol] 2024 Apr; Vol. 25 (4), pp. 474-487.
Publication Type: Multicenter Study; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gedatolisib in combination with palbociclib and endocrine therapy in women with hormone receptor-positive, HER2-negative advanced breast cancer: results from the dose expansion groups of an open-label, phase 1b study.
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  Data: <searchLink fieldCode="AU" term="%22Layman+RM%22">Layman RM</searchLink>; Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: rlayman@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Han+HS%22">Han HS</searchLink>; Moffit Cancer Center, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Rugo+HS%22">Rugo HS</searchLink>; Division of Hematology and Oncology, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stringer-Reasor+EM%22">Stringer-Reasor EM</searchLink>; Division of Hematology Oncology, Department of Medicine, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Specht+JM%22">Specht JM</searchLink>; Division of Hematology and Oncology, Fred Hutch Cancer Center, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Dees+EC%22">Dees EC</searchLink>; Division of Oncology, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kabos+P%22">Kabos P</searchLink>; Division of Medical Oncology, University of Colorado Hospital, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Suzuki+S%22">Suzuki S</searchLink>; Celcuity, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Mutka+SC%22">Mutka SC</searchLink>; Celcuity, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Sullivan+BF%22">Sullivan BF</searchLink>; Celcuity, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Gorbatchevsky+I%22">Gorbatchevsky I</searchLink>; Celcuity, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Wesolowski+R%22">Wesolowski R</searchLink>; Department. of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
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  Data: <searchLink fieldCode="JN" term="%22100957246%22">The Lancet. Oncology</searchLink> [Lancet Oncol] 2024 Apr; Vol. 25 (4), pp. 474-487.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lancet+Pub%2E+Group%22">Lancet Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100957246 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-5488 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214702045%22">14702045 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/S1470-2045(24)00034-2
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              Text: 2024 Apr
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