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Long-term safety and effectiveness of roflumilast cream 0.3% in adults with chronic plaque psoriasis: A 52-week, phase 2, open-label trial.

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Title: Long-term safety and effectiveness of roflumilast cream 0.3% in adults with chronic plaque psoriasis: A 52-week, phase 2, open-label trial.
Authors: Stein Gold L; Henry Ford Medical Center, Detroit, Michigan. Electronic address: lstein1@hfhs.org., Adam DN; CCA Medical Research, Toronto, Ontario, Canada; Probity Medical Research, Toronto, Ontario, Canada; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Albrecht L; Enverus Medical Research, Surrey, British Columbia, Canada., Alonso-Llamazares J; Driven Research LLC, Coral Gables, Florida., Ferris LK; Department of Dermatology, University of Pittsburgh, Pittsburgh, Pennsylvania., Gooderham MJ; SkiN Centre for Dermatology, Peterborough, Ontario, Canada; Probity Medical Research, Peterborough, Ontario, Canada; Queen's University, Peterborough, Ontario, Canada., Hong HC; Probity Medical Research, Surrey, British Columbia, Canada; Department of Dermatology and Skin Science, University of British Columbia, Surrey, British Columbia, Canada., Kempers SE; Minnesota Clinical Study Center, Fridley, Minnesota., Kircik LH; Icahn School of Medicine at Mount Sinai, New York, New York; Indiana Medical Center, Indianapolis, Indiana; Physicians Skin Care, PLLC, Louisville, Kentucky; Skin Sciences, PLLC, Louisville, Kentucky., Lebwohl M; Icahn School of Medicine at Mount Sinai, New York, New York., Loo WJ; DermEffects, London, Ontario, Canada; Probity Medical Research, London, Ontario, Canada; Western University, London, Ontario, Canada., Nahm WK; University of California, San Diego, School of Medicine, San Diego, California., Papp KA; Probity Medical Research, Waterloo, Ontario, Canada; Alliance Clinical Trials, Waterloo, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada., Stewart D; Michigan Center for Skin Care Research, Clinton Township, Michigan., Toth DP; XLR8 Medical Research, Windsor, Ontario, Canada; Probity Medical Research, Windsor, Ontario, Canada., Zirwas M; Dermatologists of the Central States, Bexley, Ohio; Probity Medical Research, Bexley, Ohio; Ohio University, Bexley, Ohio., Krupa D; Arcutis Biotherapeutics, Inc., Westlake Village, California., Snyder S; Arcutis Biotherapeutics, Inc., Westlake Village, California., Burnett P; Arcutis Biotherapeutics, Inc., Westlake Village, California., Higham R; Arcutis Biotherapeutics, Inc., Westlake Village, California., Berk DR; Arcutis Biotherapeutics, Inc., Westlake Village, California.
Source: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2024 Aug; Vol. 91 (2), pp. 273-280. Date of Electronic Publication: 2024 Mar 29.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 7907132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6787 (Electronic) Linking ISSN: 01909622 NLM ISO Abbreviation: J Am Acad Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Long-term safety and effectiveness of roflumilast cream 0.3% in adults with chronic plaque psoriasis: A 52-week, phase 2, open-label trial.
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  Data: <searchLink fieldCode="AU" term="%22Stein+Gold+L%22">Stein Gold L</searchLink>; Henry Ford Medical Center, Detroit, Michigan. Electronic address: lstein1@hfhs.org.<br /><searchLink fieldCode="AU" term="%22Adam+DN%22">Adam DN</searchLink>; CCA Medical Research, Toronto, Ontario, Canada; Probity Medical Research, Toronto, Ontario, Canada; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Albrecht+L%22">Albrecht L</searchLink>; Enverus Medical Research, Surrey, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Alonso-Llamazares+J%22">Alonso-Llamazares J</searchLink>; Driven Research LLC, Coral Gables, Florida.<br /><searchLink fieldCode="AU" term="%22Ferris+LK%22">Ferris LK</searchLink>; Department of Dermatology, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Gooderham+MJ%22">Gooderham MJ</searchLink>; SkiN Centre for Dermatology, Peterborough, Ontario, Canada; Probity Medical Research, Peterborough, Ontario, Canada; Queen's University, Peterborough, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Hong+HC%22">Hong HC</searchLink>; Probity Medical Research, Surrey, British Columbia, Canada; Department of Dermatology and Skin Science, University of British Columbia, Surrey, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Kempers+SE%22">Kempers SE</searchLink>; Minnesota Clinical Study Center, Fridley, Minnesota.<br /><searchLink fieldCode="AU" term="%22Kircik+LH%22">Kircik LH</searchLink>; Icahn School of Medicine at Mount Sinai, New York, New York; Indiana Medical Center, Indianapolis, Indiana; Physicians Skin Care, PLLC, Louisville, Kentucky; Skin Sciences, PLLC, Louisville, Kentucky.<br /><searchLink fieldCode="AU" term="%22Lebwohl+M%22">Lebwohl M</searchLink>; Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Loo+WJ%22">Loo WJ</searchLink>; DermEffects, London, Ontario, Canada; Probity Medical Research, London, Ontario, Canada; Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Nahm+WK%22">Nahm WK</searchLink>; University of California, San Diego, School of Medicine, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Papp+KA%22">Papp KA</searchLink>; Probity Medical Research, Waterloo, Ontario, Canada; Alliance Clinical Trials, Waterloo, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Stewart+D%22">Stewart D</searchLink>; Michigan Center for Skin Care Research, Clinton Township, Michigan.<br /><searchLink fieldCode="AU" term="%22Toth+DP%22">Toth DP</searchLink>; XLR8 Medical Research, Windsor, Ontario, Canada; Probity Medical Research, Windsor, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zirwas+M%22">Zirwas M</searchLink>; Dermatologists of the Central States, Bexley, Ohio; Probity Medical Research, Bexley, Ohio; Ohio University, Bexley, Ohio.<br /><searchLink fieldCode="AU" term="%22Krupa+D%22">Krupa D</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, California.<br /><searchLink fieldCode="AU" term="%22Snyder+S%22">Snyder S</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, California.<br /><searchLink fieldCode="AU" term="%22Burnett+P%22">Burnett P</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, California.<br /><searchLink fieldCode="AU" term="%22Higham+R%22">Higham R</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, California.<br /><searchLink fieldCode="AU" term="%22Berk+DR%22">Berk DR</searchLink>; Arcutis Biotherapeutics, Inc., Westlake Village, California.
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  Data: <searchLink fieldCode="JN" term="%227907132%22">Journal of the American Academy of Dermatology</searchLink> [J Am Acad Dermatol] 2024 Aug; Vol. 91 (2), pp. 273-280. <i>Date of Electronic Publication: </i>2024 Mar 29.
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  Data: Journal Article; Clinical Trial, Phase II; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7907132 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6787 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201909622%22">01909622 </searchLink><i>NLM ISO Abbreviation: </i>J Am Acad Dermatol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jaad.2024.03.030
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      – Code: eng
        Text: English
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        StartPage: 273
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      – TitleFull: Long-term safety and effectiveness of roflumilast cream 0.3% in adults with chronic plaque psoriasis: A 52-week, phase 2, open-label trial.
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              Text: 2024 Aug
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