Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.
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| Title: | Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma. |
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| Authors: | Zhou Y; Molecular Medicine Partnership Unit (MMPU), Heidelberg University and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany., Ray PS; Molecular Medicine Partnership Unit (MMPU), Heidelberg University and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany., Zhu J; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Stein F; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Rettel M; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Sekaran T; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Sahadevan S; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Perez-Perri JI; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Roth EK; Molecular Medicine Partnership Unit (MMPU), Heidelberg University and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany., Myklebost O; Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., Meza-Zepeda LA; Genomics Core Facility, Department of Core Facilities, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., von Deimling A; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), and Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany., Fu C; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany., Brosig AN; Molecular Medicine Partnership Unit (MMPU), Heidelberg University and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany.; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Boye K; Department of Oncology, Oslo University Hospital, Oslo, Norway., Nathrath M; Department of Pediatrics and Children's Cancer Research Center, Technical University of Munich, School of Medicine, Munich, Germany.; Pediatric Hematology and Oncology, Klinikum Kassel, Kassel, Germany.; Department of Pediatric Oncology, Hematology and Immunology, Olga Hospital, Stuttgart, Germany., Blattmann C; Department of Pediatric Oncology, Hematology and Immunology, Olga Hospital, Stuttgart, Germany., Lehner B; Department of Orthopaedics, Trauma Surgery and Paraplegiology, Heidelberg University Hospital, Heidelberg, Germany., Hentze MW; Molecular Medicine Partnership Unit (MMPU), Heidelberg University and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. hentze@embl.org.; European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. hentze@embl.org., Kulozik AE; Molecular Medicine Partnership Unit (MMPU), Heidelberg University and European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. andreas.kulozik@med.uni-heidelberg.de.; Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany. andreas.kulozik@med.uni-heidelberg.de.; Clinical Cooperation Unit Pediatric Leukemia, German Cancer Research Center (DKFZ) and Heidelberg University, Heidelberg, Germany. andreas.kulozik@med.uni-heidelberg.de. |
| Source: | Nature communications [Nat Commun] 2024 Apr 01; Vol. 15 (1), pp. 2810. Date of Electronic Publication: 2024 Apr 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-024-47031-y |
