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SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system.

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Title: SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system.
Authors: Hatch CJ; Department of Biomedical Engineering, University of California, Irvine, CA, United States., Piombo SD; Department of Pediatrics, School of Medicine, Institute for Clinical and Translational Science, University of California, Irvine, CA, United States., Fang JS; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States., Gach JS; Division of Infectious Diseases, School of Medicine, University of California, Irvine, CA, United States., Ewald ML; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States., Van Trigt WK; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States., Coon BG; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States., Tong JM; Department of Biomedical Engineering, University of California, Irvine, CA, United States., Forthal DN; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.; Division of Infectious Diseases, School of Medicine, University of California, Irvine, CA, United States., Hughes CCW; Department of Biomedical Engineering, University of California, Irvine, CA, United States.; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.
Source: Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2024 Mar 21; Vol. 11, pp. 1360364. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653388 Publication Model: eCollection Cited Medium: Print ISSN: 2297-055X (Print) Linking ISSN: 2297055X NLM ISO Abbreviation: Front Cardiovasc Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system.
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  Data: <searchLink fieldCode="AU" term="%22Hatch+CJ%22">Hatch CJ</searchLink>; Department of Biomedical Engineering, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Piombo+SD%22">Piombo SD</searchLink>; Department of Pediatrics, School of Medicine, Institute for Clinical and Translational Science, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Fang+JS%22">Fang JS</searchLink>; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Gach+JS%22">Gach JS</searchLink>; Division of Infectious Diseases, School of Medicine, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Ewald+ML%22">Ewald ML</searchLink>; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Van+Trigt+WK%22">Van Trigt WK</searchLink>; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Coon+BG%22">Coon BG</searchLink>; Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.<br /><searchLink fieldCode="AU" term="%22Tong+JM%22">Tong JM</searchLink>; Department of Biomedical Engineering, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Forthal+DN%22">Forthal DN</searchLink>; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.; Division of Infectious Diseases, School of Medicine, University of California, Irvine, CA, United States.<br /><searchLink fieldCode="AU" term="%22Hughes+CCW%22">Hughes CCW</searchLink>; Department of Biomedical Engineering, University of California, Irvine, CA, United States.; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+S%2EA%22">Frontiers Media S.A </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101653388 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2297-055X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222297055X%22">2297055X </searchLink><i>NLM ISO Abbreviation: </i>Front Cardiovasc Med <i>Subsets: </i>PubMed not MEDLINE
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