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Timing of radiotherapy (RT) after radical prostatectomy (RP): long-term outcomes in the RADICALS-RT trial (NCT00541047).

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Title: Timing of radiotherapy (RT) after radical prostatectomy (RP): long-term outcomes in the RADICALS-RT trial (NCT00541047).
Authors: Parker CC; Institute of Cancer Research, Royal Marsden NHS Foundation Trust, Sutton, UK. Electronic address: chris.parker@rmh.nhs.uk., Petersen PM; Department of Oncology, Copenhagen Prostate Cancer Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Cook AD; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London., Clarke NW; Department of Urology, The Christie NHS Foundation Trust, Manchester; Manchester Cancer Research Centre, The University of Manchester, Manchester; Department of Urology, Salford Royal NHS Foundation Trust, Manchester, UK, Department of Urology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK., Catton C; Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Cross WR; Department of Urology, St James's University Hospital, Leeds., Kynaston H; Division of Cancer and Genetics, Cardiff University, Cardiff, UK., Parulekar WR; Canadian Cancer Trials Group, Queen's University, Kingston, Canada., Persad RA; Department of Urology, Bristol Urological Institute, Bristol, UK., Saad F; Department of Urology, Centre Hospitalier de l'Université de Montréal, Montreal, Canada., Bower L; Guy's and St Thomas' NHS Foundation Trust, London; Institute of Cancer Research, Royal Marsden NHS Foundation Trust, London, UK., Durkan GC; Department of Urology, University Hospital Galway, Galway, Ireland., Logue J; Department of Oncology, The Christie Hospital NHS FT, Wilmslow Road, Manchester., Maniatis C; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London., Noor D; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London., Payne H; The Prostate Centre, London., Anderson J; St James's Institute of Oncology, Leeds., Bahl AK; Bristol Haematology and Oncology Centre, University Hospitals Bristol & Weston NHS Trust, Bristol., Bashir F; Queen's Centre for Oncology, Castle Hill Hospital, Hull University Teaching Hospitals NHS Trust, Cottingham, UK., Bottomley DM; St James's Institute of Oncology, Leeds., Brasso K; Department of Urology, Copenhagen Prostate Cancer Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Capaldi L; Worcester Oncology Centre, Worcestershire Acute NHS Hospitals Trust, Worcester., Chung C; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London., Cooke PW; Department of Urology, The Royal Wolverhampton NHS Trust, Wolverhampton., Donohue JF; Department of Urology, Maidstone and Tunbridge Wells NHS Trust, Maidstone., Eddy B; East Kent University Hospitals Foundation Trust, Kent., Heath CM; Department of Clinical Oncology, University Hospital Southampton NHS Foundation Trust, Southampton., Henderson A; Department of Urology, Maidstone and Tunbridge Wells NHS Trust, Maidstone., Henry A; Leeds Institute of Medical Research, University of Leeds, Leeds., Jaganathan R; Department of Urology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Jakobsen H; Department of Urology, Herlev University Hospital, Herlev, Denmark., James ND; Institute of Cancer Research, Royal Marsden NHS Foundation Trust, London, UK., Joseph J; Leeds Teaching Hospitals; York and Scarborough Teaching Hospitals, York., Lees K; Kent Oncology Centre, Maidstone and Tunbridge Wells NHS Trust, Maidstone., Lester J; South West Wales Cancer Centre, Singleton Hospital, Swansea, UK., Lindberg H; Department of Oncology, Herlev University Hospital, Herlev, Denmark., Makar A; Department of Urology, Worcestershire Acute Hospitals Trust, Worcester., Morris SL; Guy's and St Thomas' NHS Foundation Trust, London., Oommen N; Wrexham Maelor Hospital, Wrexham., Ostler P; Department of Urology, Hillingdon Hospitals NHS Foundation Trust, Hillingdon, London., Owen L; Bradford Royal Infirmary, Bradford; Leeds Cancer Centre, Leeds., Patel P; Department of Urology, University College London Hospitals, London., Pope A; Department of Urology, Hillingdon Hospitals NHS Foundation Trust, Hillingdon, London., Popert R; Guy's and St Thomas' NHS Foundation Trust, London., Raman R; Kent Oncology Centre, Kent & Canterbury Hospital, Canterbury., Ramani V; Department of Urology, The Christie NHS Foundation Trust, Manchester., Røder A; Department of Urology, Copenhagen Prostate Cancer Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen., Sayers I; Deanesly Centre, New Cross Hospital, Wolverhampton., Simms M; Department of Urology, Hull University Hospitals NHS Trust, Hull., Srinivasan V; Glan Clwyd Hospital, Betsi Cadwaladr University Health Board, Rhyl., Sundaram S; Department of Urology, Mid Yorkshire Teaching Hospital, Wakefield., Tarver KL; Department of Oncology, Queen's Hospital, Romford., Tran A; Department of Oncology, The Christie Hospital NHS FT, Wilmslow Road, Manchester., Wells P; Barts Cancer Centre, St Bartholomews Hospital, London., Wilson J; Royal Gwent Hospital, Newport., Zarkar AM; Department of Oncology, University Hospitals Birmingham, Birmingham, UK., Parmar MKB; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London., Sydes MR; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London. Electronic address: mrcctu.radicals@ucl.ac.uk.
Corporate Authors: RADICALS investigators
Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2024 Jul; Vol. 35 (7), pp. 656-666. Date of Electronic Publication: 2024 Apr 05.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Timing of radiotherapy (RT) after radical prostatectomy (RP): long-term outcomes in the RADICALS-RT trial (NCT00541047).
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  Data: <searchLink fieldCode="AU" term="%22Parker+CC%22">Parker CC</searchLink>; Institute of Cancer Research, Royal Marsden NHS Foundation Trust, Sutton, UK. Electronic address: chris.parker@rmh.nhs.uk.<br /><searchLink fieldCode="AU" term="%22Petersen+PM%22">Petersen PM</searchLink>; Department of Oncology, Copenhagen Prostate Cancer Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Cook+AD%22">Cook AD</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London.<br /><searchLink fieldCode="AU" term="%22Clarke+NW%22">Clarke NW</searchLink>; Department of Urology, The Christie NHS Foundation Trust, Manchester; Manchester Cancer Research Centre, The University of Manchester, Manchester; Department of Urology, Salford Royal NHS Foundation Trust, Manchester, UK, Department of Urology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Catton+C%22">Catton C</searchLink>; Department of Radiation Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Cross+WR%22">Cross WR</searchLink>; Department of Urology, St James's University Hospital, Leeds.<br /><searchLink fieldCode="AU" term="%22Kynaston+H%22">Kynaston H</searchLink>; Division of Cancer and Genetics, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Parulekar+WR%22">Parulekar WR</searchLink>; Canadian Cancer Trials Group, Queen's University, Kingston, Canada.<br /><searchLink fieldCode="AU" term="%22Persad+RA%22">Persad RA</searchLink>; Department of Urology, Bristol Urological Institute, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Saad+F%22">Saad F</searchLink>; Department of Urology, Centre Hospitalier de l'Université de Montréal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Bower+L%22">Bower L</searchLink>; Guy's and St Thomas' NHS Foundation Trust, London; Institute of Cancer Research, Royal Marsden NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Durkan+GC%22">Durkan GC</searchLink>; Department of Urology, University Hospital Galway, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Logue+J%22">Logue J</searchLink>; Department of Oncology, The Christie Hospital NHS FT, Wilmslow Road, Manchester.<br /><searchLink fieldCode="AU" term="%22Maniatis+C%22">Maniatis C</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London.<br /><searchLink fieldCode="AU" term="%22Noor+D%22">Noor D</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London.<br /><searchLink fieldCode="AU" term="%22Payne+H%22">Payne H</searchLink>; The Prostate Centre, London.<br /><searchLink fieldCode="AU" term="%22Anderson+J%22">Anderson J</searchLink>; St James's Institute of Oncology, Leeds.<br /><searchLink fieldCode="AU" term="%22Bahl+AK%22">Bahl AK</searchLink>; Bristol Haematology and Oncology Centre, University Hospitals Bristol & Weston NHS Trust, Bristol.<br /><searchLink fieldCode="AU" term="%22Bashir+F%22">Bashir F</searchLink>; Queen's Centre for Oncology, Castle Hill Hospital, Hull University Teaching Hospitals NHS Trust, Cottingham, UK.<br /><searchLink fieldCode="AU" term="%22Bottomley+DM%22">Bottomley DM</searchLink>; St James's Institute of Oncology, Leeds.<br /><searchLink fieldCode="AU" term="%22Brasso+K%22">Brasso K</searchLink>; Department of Urology, Copenhagen Prostate Cancer Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Capaldi+L%22">Capaldi L</searchLink>; Worcester Oncology Centre, Worcestershire Acute NHS Hospitals Trust, Worcester.<br /><searchLink fieldCode="AU" term="%22Chung+C%22">Chung C</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London.<br /><searchLink fieldCode="AU" term="%22Cooke+PW%22">Cooke PW</searchLink>; Department of Urology, The Royal Wolverhampton NHS Trust, Wolverhampton.<br /><searchLink fieldCode="AU" term="%22Donohue+JF%22">Donohue JF</searchLink>; Department of Urology, Maidstone and Tunbridge Wells NHS Trust, Maidstone.<br /><searchLink fieldCode="AU" term="%22Eddy+B%22">Eddy B</searchLink>; East Kent University Hospitals Foundation Trust, Kent.<br /><searchLink fieldCode="AU" term="%22Heath+CM%22">Heath CM</searchLink>; Department of Clinical Oncology, University Hospital Southampton NHS Foundation Trust, Southampton.<br /><searchLink fieldCode="AU" term="%22Henderson+A%22">Henderson A</searchLink>; Department of Urology, Maidstone and Tunbridge Wells NHS Trust, Maidstone.<br /><searchLink fieldCode="AU" term="%22Henry+A%22">Henry A</searchLink>; Leeds Institute of Medical Research, University of Leeds, Leeds.<br /><searchLink fieldCode="AU" term="%22Jaganathan+R%22">Jaganathan R</searchLink>; Department of Urology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Jakobsen+H%22">Jakobsen H</searchLink>; Department of Urology, Herlev University Hospital, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22James+ND%22">James ND</searchLink>; Institute of Cancer Research, Royal Marsden NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Joseph+J%22">Joseph J</searchLink>; Leeds Teaching Hospitals; York and Scarborough Teaching Hospitals, York.<br /><searchLink fieldCode="AU" term="%22Lees+K%22">Lees K</searchLink>; Kent Oncology Centre, Maidstone and Tunbridge Wells NHS Trust, Maidstone.<br /><searchLink fieldCode="AU" term="%22Lester+J%22">Lester J</searchLink>; South West Wales Cancer Centre, Singleton Hospital, Swansea, UK.<br /><searchLink fieldCode="AU" term="%22Lindberg+H%22">Lindberg H</searchLink>; Department of Oncology, Herlev University Hospital, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Makar+A%22">Makar A</searchLink>; Department of Urology, Worcestershire Acute Hospitals Trust, Worcester.<br /><searchLink fieldCode="AU" term="%22Morris+SL%22">Morris SL</searchLink>; Guy's and St Thomas' NHS Foundation Trust, London.<br /><searchLink fieldCode="AU" term="%22Oommen+N%22">Oommen N</searchLink>; Wrexham Maelor Hospital, Wrexham.<br /><searchLink fieldCode="AU" term="%22Ostler+P%22">Ostler P</searchLink>; Department of Urology, Hillingdon Hospitals NHS Foundation Trust, Hillingdon, London.<br /><searchLink fieldCode="AU" term="%22Owen+L%22">Owen L</searchLink>; Bradford Royal Infirmary, Bradford; Leeds Cancer Centre, Leeds.<br /><searchLink fieldCode="AU" term="%22Patel+P%22">Patel P</searchLink>; Department of Urology, University College London Hospitals, London.<br /><searchLink fieldCode="AU" term="%22Pope+A%22">Pope A</searchLink>; Department of Urology, Hillingdon Hospitals NHS Foundation Trust, Hillingdon, London.<br /><searchLink fieldCode="AU" term="%22Popert+R%22">Popert R</searchLink>; Guy's and St Thomas' NHS Foundation Trust, London.<br /><searchLink fieldCode="AU" term="%22Raman+R%22">Raman R</searchLink>; Kent Oncology Centre, Kent & Canterbury Hospital, Canterbury.<br /><searchLink fieldCode="AU" term="%22Ramani+V%22">Ramani V</searchLink>; Department of Urology, The Christie NHS Foundation Trust, Manchester.<br /><searchLink fieldCode="AU" term="%22Røder+A%22">Røder A</searchLink>; Department of Urology, Copenhagen Prostate Cancer Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen.<br /><searchLink fieldCode="AU" term="%22Sayers+I%22">Sayers I</searchLink>; Deanesly Centre, New Cross Hospital, Wolverhampton.<br /><searchLink fieldCode="AU" term="%22Simms+M%22">Simms M</searchLink>; Department of Urology, Hull University Hospitals NHS Trust, Hull.<br /><searchLink fieldCode="AU" term="%22Srinivasan+V%22">Srinivasan V</searchLink>; Glan Clwyd Hospital, Betsi Cadwaladr University Health Board, Rhyl.<br /><searchLink fieldCode="AU" term="%22Sundaram+S%22">Sundaram S</searchLink>; Department of Urology, Mid Yorkshire Teaching Hospital, Wakefield.<br /><searchLink fieldCode="AU" term="%22Tarver+KL%22">Tarver KL</searchLink>; Department of Oncology, Queen's Hospital, Romford.<br /><searchLink fieldCode="AU" term="%22Tran+A%22">Tran A</searchLink>; Department of Oncology, The Christie Hospital NHS FT, Wilmslow Road, Manchester.<br /><searchLink fieldCode="AU" term="%22Wells+P%22">Wells P</searchLink>; Barts Cancer Centre, St Bartholomews Hospital, London.<br /><searchLink fieldCode="AU" term="%22Wilson+J%22">Wilson J</searchLink>; Royal Gwent Hospital, Newport.<br /><searchLink fieldCode="AU" term="%22Zarkar+AM%22">Zarkar AM</searchLink>; Department of Oncology, University Hospitals Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Parmar+MKB%22">Parmar MKB</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London.<br /><searchLink fieldCode="AU" term="%22Sydes+MR%22">Sydes MR</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, London. 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