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ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport.

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Title: ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport.
Authors: Liu B; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK., Azfar M; Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, Box 802, 3000 Leuven, Belgium., Legchenko E; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK., West JA; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge CB2 0AW, UK.; Division of Gastroenterology and Hepatology, Department of Medicine, Hills Road, Cambridge CB2 0QQ, UK.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK., Martin S; Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, Box 802, 3000 Leuven, Belgium., Van den Haute C; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Herestraat 49, Box 1023, 3000 Leuven, Belgium.; Leuven Viral Vector Core, KU Leuven, Herestraat 49, Box 1023, 3000 Leuven, Belgium., Baekelandt V; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Herestraat 49, Box 1023, 3000 Leuven, Belgium., Wharton J; Faculty of Medicine, National Heart and Lung Institute, ICTEM Building, Imperial College, Du Cane Road, London W12 0NN, UK., Howard L; Faculty of Medicine, National Heart and Lung Institute, ICTEM Building, Imperial College, Du Cane Road, London W12 0NN, UK., Wilkins MR; Faculty of Medicine, National Heart and Lung Institute, ICTEM Building, Imperial College, Du Cane Road, London W12 0NN, UK., Vangheluwe P; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK., Morrell NW; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK., Upton PD; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK.
Source: Cardiovascular research [Cardiovasc Res] 2024 May 29; Vol. 120 (7), pp. 756-768.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport.
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  Data: <searchLink fieldCode="AU" term="%22Liu+B%22">Liu B</searchLink>; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK.<br /><searchLink fieldCode="AU" term="%22Azfar+M%22">Azfar M</searchLink>; Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, Box 802, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Legchenko+E%22">Legchenko E</searchLink>; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK.<br /><searchLink fieldCode="AU" term="%22West+JA%22">West JA</searchLink>; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge CB2 0AW, UK.; Division of Gastroenterology and Hepatology, Department of Medicine, Hills Road, Cambridge CB2 0QQ, UK.; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Martin+S%22">Martin S</searchLink>; Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, Box 802, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+den+Haute+C%22">Van den Haute C</searchLink>; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Herestraat 49, Box 1023, 3000 Leuven, Belgium.; Leuven Viral Vector Core, KU Leuven, Herestraat 49, Box 1023, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Baekelandt+V%22">Baekelandt V</searchLink>; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, KU Leuven, Herestraat 49, Box 1023, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Wharton+J%22">Wharton J</searchLink>; Faculty of Medicine, National Heart and Lung Institute, ICTEM Building, Imperial College, Du Cane Road, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Howard+L%22">Howard L</searchLink>; Faculty of Medicine, National Heart and Lung Institute, ICTEM Building, Imperial College, Du Cane Road, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Wilkins+MR%22">Wilkins MR</searchLink>; Faculty of Medicine, National Heart and Lung Institute, ICTEM Building, Imperial College, Du Cane Road, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Vangheluwe+P%22">Vangheluwe P</searchLink>; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Morrell+NW%22">Morrell NW</searchLink>; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK.<br /><searchLink fieldCode="AU" term="%22Upton+PD%22">Upton PD</searchLink>; Section of Cardio and Respiratory Medicine, Department of Medicine, Victor Phillip Dahdaleh Heart and Lung Research Institute, Papworth Road, Cambridge CB2 0BB, UK.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+Journals%22">Oxford Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0077427 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1755-3245 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200086363%22">00086363 </searchLink><i>NLM ISO Abbreviation: </i>Cardiovasc Res <i>Subsets: </i>MEDLINE
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        Value: 10.1093/cvr/cvae068
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