Bright light therapy versus physical exercise to prevent co-occurring depression in adolescents and young adults with attention-deficit/hyperactivity disorder: a multicentre, three-arm, randomised controlled, pilot phase-IIa trial.

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Title: Bright light therapy versus physical exercise to prevent co-occurring depression in adolescents and young adults with attention-deficit/hyperactivity disorder: a multicentre, three-arm, randomised controlled, pilot phase-IIa trial.
Authors: Mayer JS; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany. mayer@psych.uni-frankfurt.de., Kohlhas L; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany., Stermann J; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany., Medda J; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany., Brandt GA; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Grimm O; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany., Pawley AD; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Asherson P; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Sanchez JP; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain., Richarte V; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain.; Biomedical Network Research Centre On Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain., Bergsma D; Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands., Koch ED; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.; Mental mHealth Lab, Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany., Muntaner-Mas A; GICAFE 'Physical Activity and Exercise Sciences Research Group', Faculty of Education, University of Balearic Islands, Palma, Spain.; Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain., Ebner-Priemer UW; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Mental mHealth Lab, Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.; German Center for Mental Health (DZPG), partner site Mannheim, Mannheim, Germany., Kieser M; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany., Retz W; Department of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.; Institute for Forensic Psychology and Psychiatry, Saarland University Medical Center, Homburg/Saar, Germany., Ortega FB; Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.; CIBEROBN Physiopathology of Obesity and Nutrition, Granada, Spain.; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Colla M; Department of Psychiatry, University Hospital Rostock, Rostock, Germany.; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland., Buitelaar JK; Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands., Kuntsi J; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Ramos-Quiroga JA; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain.; Biomedical Network Research Centre On Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain.; Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany., Freitag CM; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.
Source: European archives of psychiatry and clinical neuroscience [Eur Arch Psychiatry Clin Neurosci] 2025 Apr; Vol. 275 (3), pp. 653-665. Date of Electronic Publication: 2024 Apr 16.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9103030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-8491 (Electronic) Linking ISSN: 09401334 NLM ISO Abbreviation: Eur Arch Psychiatry Clin Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bright light therapy versus physical exercise to prevent co-occurring depression in adolescents and young adults with attention-deficit/hyperactivity disorder: a multicentre, three-arm, randomised controlled, pilot phase-IIa trial.
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  Data: <searchLink fieldCode="AU" term="%22Mayer+JS%22">Mayer JS</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany. mayer@psych.uni-frankfurt.de.<br /><searchLink fieldCode="AU" term="%22Kohlhas+L%22">Kohlhas L</searchLink>; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Stermann+J%22">Stermann J</searchLink>; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Medda+J%22">Medda J</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Brandt+GA%22">Brandt GA</searchLink>; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Grimm+O%22">Grimm O</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Pawley+AD%22">Pawley AD</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Asherson+P%22">Asherson P</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Sanchez+JP%22">Sanchez JP</searchLink>; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Richarte+V%22">Richarte V</searchLink>; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain.; Biomedical Network Research Centre On Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Bergsma+D%22">Bergsma D</searchLink>; Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koch+ED%22">Koch ED</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.; Mental mHealth Lab, Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Muntaner-Mas+A%22">Muntaner-Mas A</searchLink>; GICAFE 'Physical Activity and Exercise Sciences Research Group', Faculty of Education, University of Balearic Islands, Palma, Spain.; Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Ebner-Priemer+UW%22">Ebner-Priemer UW</searchLink>; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Mental mHealth Lab, Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.; German Center for Mental Health (DZPG), partner site Mannheim, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Kieser+M%22">Kieser M</searchLink>; Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Retz+W%22">Retz W</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.; Institute for Forensic Psychology and Psychiatry, Saarland University Medical Center, Homburg/Saar, Germany.<br /><searchLink fieldCode="AU" term="%22Ortega+FB%22">Ortega FB</searchLink>; Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.; CIBEROBN Physiopathology of Obesity and Nutrition, Granada, Spain.; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.<br /><searchLink fieldCode="AU" term="%22Colla+M%22">Colla M</searchLink>; Department of Psychiatry, University Hospital Rostock, Rostock, Germany.; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Buitelaar+JK%22">Buitelaar JK</searchLink>; Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kuntsi+J%22">Kuntsi J</searchLink>; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ramos-Quiroga+JA%22">Ramos-Quiroga JA</searchLink>; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute, Barcelona, Catalonia, Spain.; Biomedical Network Research Centre On Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain.; Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Reif+A%22">Reif A</searchLink>; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Freitag+CM%22">Freitag CM</searchLink>; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.
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  Data: <searchLink fieldCode="JN" term="%229103030%22">European archives of psychiatry and clinical neuroscience</searchLink> [Eur Arch Psychiatry Clin Neurosci] 2025 Apr; Vol. 275 (3), pp. 653-665. <i>Date of Electronic Publication: </i>2024 Apr 16.
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