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Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection.

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Title: Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection.
Authors: Liu C; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK., Das R; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK., Dijokaite-Guraliuc A; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK., Zhou D; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.; College of Life Sciences, Zhejiang University, Hangzhou, 310058, China., Mentzer AJ; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Supasa P; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK., Selvaraj M; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK., Duyvesteyn HME; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK., Ritter TG; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent and Greenwich Chatham Maritime, Kent, ME4 4TB, UK., Klenerman P; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Peter Medawar Building for Pathogen Research, Oxford, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK., Dunachie SJ; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Peter Medawar Building for Pathogen Research, Oxford, UK.; Nuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand., Paterson NG; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK., Williams MA; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK., Hall DR; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK., Fry EE; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK. liz@strubi.ox.ac.uk., Mongkolsapaya J; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. juthathip.mongkolsapaya@well.ox.ac.uk.; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK. juthathip.mongkolsapaya@well.ox.ac.uk.; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand. juthathip.mongkolsapaya@well.ox.ac.uk., Ren J; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK. ren@strubi.ox.ac.uk., Stuart DI; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. dave@strubi.ox.ac.uk.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK. dave@strubi.ox.ac.uk.; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK. dave@strubi.ox.ac.uk., Screaton GR; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. gavin.screaton@medsci.ox.ac.uk.; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK. gavin.screaton@medsci.ox.ac.uk.
Source: Nature communications [Nat Commun] 2024 Apr 16; Vol. 15 (1), pp. 3284. Date of Electronic Publication: 2024 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection.
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  Data: <searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Das+R%22">Das R</searchLink>; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dijokaite-Guraliuc+A%22">Dijokaite-Guraliuc A</searchLink>; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Zhou+D%22">Zhou D</searchLink>; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.; College of Life Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Mentzer+AJ%22">Mentzer AJ</searchLink>; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Supasa+P%22">Supasa P</searchLink>; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Selvaraj+M%22">Selvaraj M</searchLink>; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Duyvesteyn+HME%22">Duyvesteyn HME</searchLink>; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ritter+TG%22">Ritter TG</searchLink>; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Temperton+N%22">Temperton N</searchLink>; Viral Pseudotype Unit, Medway School of Pharmacy, University of Kent and Greenwich Chatham Maritime, Kent, ME4 4TB, UK.<br /><searchLink fieldCode="AU" term="%22Klenerman+P%22">Klenerman P</searchLink>; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Peter Medawar Building for Pathogen Research, Oxford, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; NIHR Oxford Biomedical Research Centre, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dunachie+SJ%22">Dunachie SJ</searchLink>; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Peter Medawar Building for Pathogen Research, Oxford, UK.; Nuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Paterson+NG%22">Paterson NG</searchLink>; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.<br /><searchLink fieldCode="AU" term="%22Williams+MA%22">Williams MA</searchLink>; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.<br /><searchLink fieldCode="AU" term="%22Hall+DR%22">Hall DR</searchLink>; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.<br /><searchLink fieldCode="AU" term="%22Fry+EE%22">Fry EE</searchLink>; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK. liz@strubi.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Mongkolsapaya+J%22">Mongkolsapaya J</searchLink>; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. juthathip.mongkolsapaya@well.ox.ac.uk.; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK. juthathip.mongkolsapaya@well.ox.ac.uk.; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand. juthathip.mongkolsapaya@well.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ren+J%22">Ren J</searchLink>; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK. ren@strubi.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Stuart+DI%22">Stuart DI</searchLink>; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. dave@strubi.ox.ac.uk.; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK. dave@strubi.ox.ac.uk.; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK. dave@strubi.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Screaton+GR%22">Screaton GR</searchLink>; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK. gavin.screaton@medsci.ox.ac.uk.; Nuffield Department of Medicine, Centre for Human Genetics, University of Oxford, Oxford, UK. gavin.screaton@medsci.ox.ac.uk.
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