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PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors.

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Title: PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors.
Authors: Sinha S; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA. ssinha@sbpdiscovery.org.; NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, San Diego, CA, USA. ssinha@sbpdiscovery.org., Vegesna R; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA., Mukherjee S; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA., Kammula AV; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.; University of Maryland, College Park, MD, USA., Dhruba SR; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA., Wu W; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Kerr DL; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., Nair NU; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA., Jones MG; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA.; Integrative Program in Quantitative Biology, University of California, San Francisco, San Francisco, CA, USA.; Whitehead Institute, Cambridge, MA, USA., Yosef N; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA., Stroganov OV; Rancho BioSciences, San Diego, CA, USA., Grishagin I; Rancho BioSciences, San Diego, CA, USA.; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Aldape KD; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA., Blakely CM; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA., Jiang P; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA., Thomas CJ; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Benes CH; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Bivona TG; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub Investigator, San Francisco, CA, USA., Schäffer AA; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA., Ruppin E; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA. eytan.ruppin@nih.gov.
Source: Nature cancer [Nat Cancer] 2024 Jun; Vol. 5 (6), pp. 938-952. Date of Electronic Publication: 2024 Apr 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Sinha+S%22">Sinha S</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA. ssinha@sbpdiscovery.org.; NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, San Diego, CA, USA. ssinha@sbpdiscovery.org.<br /><searchLink fieldCode="AU" term="%22Vegesna+R%22">Vegesna R</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Mukherjee+S%22">Mukherjee S</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kammula+AV%22">Kammula AV</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.; University of Maryland, College Park, MD, USA.<br /><searchLink fieldCode="AU" term="%22Dhruba+SR%22">Dhruba SR</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kerr+DL%22">Kerr DL</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nair+NU%22">Nair NU</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Jones+MG%22">Jones MG</searchLink>; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA.; Integrative Program in Quantitative Biology, University of California, San Francisco, San Francisco, CA, USA.; Whitehead Institute, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yosef+N%22">Yosef N</searchLink>; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stroganov+OV%22">Stroganov OV</searchLink>; Rancho BioSciences, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Grishagin+I%22">Grishagin I</searchLink>; Rancho BioSciences, San Diego, CA, USA.; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.<br /><searchLink fieldCode="AU" term="%22Aldape+KD%22">Aldape KD</searchLink>; Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Blakely+CM%22">Blakely CM</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+P%22">Jiang P</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+CJ%22">Thomas CJ</searchLink>; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.; Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Benes+CH%22">Benes CH</searchLink>; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bivona+TG%22">Bivona TG</searchLink>; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub Investigator, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schäffer+AA%22">Schäffer AA</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ruppin+E%22">Ruppin E</searchLink>; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, USA. eytan.ruppin@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2024 Jun; Vol. 5 (6), pp. 938-952. <i>Date of Electronic Publication: </i>2024 Apr 18.
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