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Defining and benchmarking open problems in single-cell analysis.

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Title: Defining and benchmarking open problems in single-cell analysis.
Authors: Luecken MD; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; Institute of Lung Health & Immunity, Helmholtz Munich; Member of the German Center for Lung Research (DZL), Munich, Germany., Gigante S; Immunai, New York, USA., Burkhardt DB; Cellarity, Inc. Somerville, USA., Cannoodt R; Data Intuitive, Lebbeke, Belgium.; Data Mining and Modelling for Biomedicine group, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium., Strobl DC; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Germany., Markov NS; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University., Zappia L; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; Department of Mathematics, School of Computing, Information and Technology, Technical University of Munich, Munich, Germany., Palla G; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Germany., Lewis W; Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA., Dimitrov D; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany., Vinyard ME; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA., Magruder DS; Department of Computer Science, Yale University, New Haven CT, USA., Andersson A; Genentech Inc.; Royal Institute of Technology (KTH), Gene Technology.; Science for Life Laboratory (SciLifeLab)., Dann E; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Qin Q; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Otto DJ; Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle WA.; Computational Biology Program, Public Health Sciences Division, Seattle WA.; Translational Data Science IRC, Fred Hutchinson Cancer Center, Seattle WA., Klein M; Apple., Botvinnik OB; Data Sciences Platform, Chan Zuckerberg Biohub, 499 Illinois St, San Francisco, CA 94158.; Bridge Bio Pharma, 3160 Porter Drive, Suite 250, Palo Alto, CA, 94304., Deconinck L; Data Mining and Modelling for Biomedicine group, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium., Waldrant K; Data Intuitive, Lebbeke, Belgium., Bloom JM; Massachusetts Institute of Technology., Pisco AO; Data Sciences Platform, Chan Zuckerberg Biohub, 499 Illinois St, San Francisco, CA 94158.; Insitro, South San Francisco., Saez-Rodriguez J; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany., Wulsin D; Immunai, New York, USA., Pinello L; Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA., Saeys Y; Data Mining and Modelling for Biomedicine group, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium.; VIB Center for AI & Computational Biology (VIB.AI), Gent, Belgium., Theis FJ; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; Department of Mathematics, School of Computing, Information and Technology, Technical University of Munich, Munich, Germany.; Cellular Genetics Programme, Wellcome Sanger Institute, Hinxton, UK (associated faculty)., Krishnaswamy S; Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA.; Department of Computer Science, Yale University, New Haven CT, USA.; Department of Genetics, Yale University, New Haven CT, USA.
Corporate Authors: Open Problems Jamboree Members
Source: Research square [Res Sq] 2024 Apr 04. Date of Electronic Publication: 2024 Apr 04.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Luecken+MD%22">Luecken MD</searchLink>; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; Institute of Lung Health & Immunity, Helmholtz Munich; Member of the German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gigante+S%22">Gigante S</searchLink>; Immunai, New York, USA.<br /><searchLink fieldCode="AU" term="%22Burkhardt+DB%22">Burkhardt DB</searchLink>; Cellarity, Inc. Somerville, USA.<br /><searchLink fieldCode="AU" term="%22Cannoodt+R%22">Cannoodt R</searchLink>; Data Intuitive, Lebbeke, Belgium.; Data Mining and Modelling for Biomedicine group, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Strobl+DC%22">Strobl DC</searchLink>; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine, Technical University of Munich, Munich, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Markov+NS%22">Markov NS</searchLink>; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University.<br /><searchLink fieldCode="AU" term="%22Zappia+L%22">Zappia L</searchLink>; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; Department of Mathematics, School of Computing, Information and Technology, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Palla+G%22">Palla G</searchLink>; Institute of computational Biology, Helmholtz Munich, Neuherberg, Germany.; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Lewis+W%22">Lewis W</searchLink>; Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA.<br /><searchLink fieldCode="AU" term="%22Dimitrov+D%22">Dimitrov D</searchLink>; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Vinyard+ME%22">Vinyard ME</searchLink>; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Magruder+DS%22">Magruder DS</searchLink>; 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Bridge Bio Pharma, 3160 Porter Drive, Suite 250, Palo Alto, CA, 94304.<br /><searchLink fieldCode="AU" term="%22Deconinck+L%22">Deconinck L</searchLink>; Data Mining and Modelling for Biomedicine group, VIB Center for Inflammation Research, Ghent, Belgium.; Department of Applied Mathematics, Computer Science, and Statistics, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Waldrant+K%22">Waldrant K</searchLink>; Data Intuitive, Lebbeke, Belgium.<br /><searchLink fieldCode="AU" term="%22Bloom+JM%22">Bloom JM</searchLink>; Massachusetts Institute of Technology.<br /><searchLink fieldCode="AU" term="%22Pisco+AO%22">Pisco AO</searchLink>; Data Sciences Platform, Chan Zuckerberg Biohub, 499 Illinois St, San Francisco, CA 94158.; Insitro, South San Francisco.<br /><searchLink fieldCode="AU" term="%22Saez-Rodriguez+J%22">Saez-Rodriguez J</searchLink>; Heidelberg University, Faculty of Medicine, and Heidelberg University Hospital, Institute for Computational Biomedicine, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wulsin+D%22">Wulsin D</searchLink>; 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Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA.; Department of Computer Science, Yale University, New Haven CT, USA.; Department of Genetics, Yale University, New Haven CT, USA.
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