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Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity.

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Title: Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity.
Authors: Vialetto E; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany., Miele S; Institut Pasteur, Université Paris Cité, Synthetic Biology, Paris, France., Goren MG; Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel., Yu J; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany., Yu Y; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany., Collias D; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany., Beamud B; Institut Pasteur, Université Paris Cité, Synthetic Biology, Paris, France., Osbelt L; Helmholtz Centre for Infection Research (HZI), 38124 Braunschweig, Germany.; German Center for Infection Research (DZIF), partner site Hannover-Braunschweig, 38124 Braunschweig, Germany., Lourenço M; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France., Strowig T; Helmholtz Centre for Infection Research (HZI), 38124 Braunschweig, Germany.; German Center for Infection Research (DZIF), partner site Hannover-Braunschweig, 38124 Braunschweig, Germany., Brisse S; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France., Barquist L; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.; Department of Biology, University of Toronto Mississauga, Mississauga, Ontario L5L 1C6, Canada.; University of Würzburg, Medical Faculty, 97080 Würzburg, Germany., Qimron U; Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel., Bikard D; Institut Pasteur, Université Paris Cité, Synthetic Biology, Paris, France., Beisel CL; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.; University of Würzburg, Medical Faculty, 97080 Würzburg, Germany.
Source: Nucleic acids research [Nucleic Acids Res] 2024 Jun 10; Vol. 52 (10), pp. 6079-6091.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity.
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  Data: <searchLink fieldCode="AU" term="%22Vialetto+E%22">Vialetto E</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Miele+S%22">Miele S</searchLink>; Institut Pasteur, Université Paris Cité, Synthetic Biology, Paris, France.<br /><searchLink fieldCode="AU" term="%22Goren+MG%22">Goren MG</searchLink>; Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Yu+Y%22">Yu Y</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Collias+D%22">Collias D</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Beamud+B%22">Beamud B</searchLink>; Institut Pasteur, Université Paris Cité, Synthetic Biology, Paris, France.<br /><searchLink fieldCode="AU" term="%22Osbelt+L%22">Osbelt L</searchLink>; Helmholtz Centre for Infection Research (HZI), 38124 Braunschweig, Germany.; German Center for Infection Research (DZIF), partner site Hannover-Braunschweig, 38124 Braunschweig, Germany.<br /><searchLink fieldCode="AU" term="%22Lourenço+M%22">Lourenço M</searchLink>; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.<br /><searchLink fieldCode="AU" term="%22Strowig+T%22">Strowig T</searchLink>; Helmholtz Centre for Infection Research (HZI), 38124 Braunschweig, Germany.; German Center for Infection Research (DZIF), partner site Hannover-Braunschweig, 38124 Braunschweig, Germany.<br /><searchLink fieldCode="AU" term="%22Brisse+S%22">Brisse S</searchLink>; Institut Pasteur, Université Paris Cité, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.<br /><searchLink fieldCode="AU" term="%22Barquist+L%22">Barquist L</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.; Department of Biology, University of Toronto Mississauga, Mississauga, Ontario L5L 1C6, Canada.; University of Würzburg, Medical Faculty, 97080 Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Qimron+U%22">Qimron U</searchLink>; Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Bikard+D%22">Bikard D</searchLink>; Institut Pasteur, Université Paris Cité, Synthetic Biology, Paris, France.<br /><searchLink fieldCode="AU" term="%22Beisel+CL%22">Beisel CL</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), 97080 Würzburg, Germany.; University of Würzburg, Medical Faculty, 97080 Würzburg, Germany.
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