Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.

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Title: Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.
Authors: Blömeke L; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany., Rehn F; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany., Kraemer-Schulien V; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany., Kutzsche J; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany., Pils M; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany., Bujnicki T; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany., Lewczuk P; Department of Psychiatry and Psychotherapy Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen Germany., Kornhuber J; Department of Psychiatry and Psychotherapy Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen Germany., Freiesleben SD; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany., Schneider LS; Department of Psychiatry and Psychotherapy Charité Berlin Germany., Preis L; Department of Psychiatry and Psychotherapy Charité Berlin Germany., Priller J; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany.; School of Medicine Department of Psychiatry and Psychotherapy Technical University of Munich Munich Germany.; University of Edinburgh and UK DRI Edinburgh UK., Spruth EJ; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany., Altenstein S; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany., Lohse A; Department of Psychiatry and Psychotherapy Charité Berlin Germany., Schneider A; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany., Fliessbach K; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany., Wiltfang J; German Center for Neurodegenerative Diseases (DZNE) Göttingen Germany.; Department of Psychiatry and Psychotherapy University Medical Center Göttingen University of Göttingen Göttingen Germany.; Department of Medical Sciences Neurosciences and Signaling Group Institute of Biomedicine (iBiMED) University of Aveiro Aveiro Portugal., Hansen N; Department of Psychiatry and Psychotherapy University Medical Center Göttingen University of Göttingen Göttingen Germany., Rostamzadeh A; Department of Psychiatry Medical Faculty University of Cologne Cologne Germany., Düzel E; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany.; Institute of Cognitive Neurology and Dementia Research (IKND) Otto-von-Guericke University Magdeburg Germany., Glanz W; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany., Incesoy EI; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany.; Institute of Cognitive Neurology and Dementia Research (IKND) Otto-von-Guericke University Magdeburg Germany.; Department for Psychiatry and Psychotherapy University Clinic Magdeburg Magdeburg Germany., Butryn M; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany., Buerger K; German Center for Neurodegenerative Diseases (DZNE, Munich) Munich Germany.; Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany., Janowitz D; Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany., Ewers M; German Center for Neurodegenerative Diseases (DZNE, Munich) Munich Germany.; Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany., Perneczky R; German Center for Neurodegenerative Diseases (DZNE, Munich) Munich Germany.; Department of Psychiatry and Psychotherapy University Hospital LMU Munich Munich Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich Munich Germany.; Ageing Epidemiology Research Unit (AGE) School of Public Health Imperial College London London UK., Rauchmann BS; Department of Psychiatry and Psychotherapy University Hospital LMU Munich Munich Germany.; Sheffield Institute for Translational Neuroscience (SITraN) University of Sheffield Sheffield UK.; Department of Neuroradiology University Hospital LMU Munich Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE) Rostock Germany.; Department of Psychosomatic Medicine Rostock University Medical Center Rostock Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE) Rostock Germany.; Department of Psychosomatic Medicine Rostock University Medical Center Rostock Germany., Goerss D; German Center for Neurodegenerative Diseases (DZNE) Rostock Germany.; Department of Psychosomatic Medicine Rostock University Medical Center Rostock Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE) Tübingen Germany.; Section for Dementia Research Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy University of Tübingen Tübingen Germany., Munk MH; German Center for Neurodegenerative Diseases (DZNE) Tübingen Germany.; Department of Psychiatry and Psychotherapy University of Tübingen Tübingen Germany., Sanzenbacher C; German Center for Neurodegenerative Diseases (DZNE) Tübingen Germany., Spottke A; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurology University of Bonn Bonn Germany., Roy-Kluth N; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany., Heneka MT; Luxembourg Centre for Systems Biomedicine (LCSB) University of Luxembourg Belvaux Luxemburg., Brosseron F; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany., Wagner M; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany., Wolfsgruber S; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany., Kleineidam L; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany., Stark M; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany., Schmid M; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Institute for Medical Biometry University Hospital Bonn Bonn Germany., Jessen F; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Psychiatry Medical Faculty University of Cologne Cologne Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) University of Cologne Köln Germany., Bannach O; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany., Willbold D; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany., Peters O; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany.
Source: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2024 Apr 25; Vol. 16 (2), pp. e12589. Date of Electronic Publication: 2024 Apr 25 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101654604 Publication Model: eCollection Cited Medium: Print ISSN: 2352-8729 (Print) Linking ISSN: 23528729 NLM ISO Abbreviation: Alzheimers Dement (Amst) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 38666085
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  Data: Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.
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  Data: <searchLink fieldCode="AU" term="%22Blömeke+L%22">Blömeke L</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany.<br /><searchLink fieldCode="AU" term="%22Rehn+F%22">Rehn F</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany.<br /><searchLink fieldCode="AU" term="%22Kraemer-Schulien+V%22">Kraemer-Schulien V</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.<br /><searchLink fieldCode="AU" term="%22Kutzsche+J%22">Kutzsche J</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.<br /><searchLink fieldCode="AU" term="%22Pils+M%22">Pils M</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany.<br /><searchLink fieldCode="AU" term="%22Bujnicki+T%22">Bujnicki T</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.<br /><searchLink fieldCode="AU" term="%22Lewczuk+P%22">Lewczuk P</searchLink>; Department of Psychiatry and Psychotherapy Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen Germany.<br /><searchLink fieldCode="AU" term="%22Kornhuber+J%22">Kornhuber J</searchLink>; Department of Psychiatry and Psychotherapy Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen Germany.<br /><searchLink fieldCode="AU" term="%22Freiesleben+SD%22">Freiesleben SD</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+LS%22">Schneider LS</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.<br /><searchLink fieldCode="AU" term="%22Preis+L%22">Preis L</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.<br /><searchLink fieldCode="AU" term="%22Priller+J%22">Priller J</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany.; School of Medicine Department of Psychiatry and Psychotherapy Technical University of Munich Munich Germany.; University of Edinburgh and UK DRI Edinburgh UK.<br /><searchLink fieldCode="AU" term="%22Spruth+EJ%22">Spruth EJ</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany.<br /><searchLink fieldCode="AU" term="%22Altenstein+S%22">Altenstein S</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany.<br /><searchLink fieldCode="AU" term="%22Lohse+A%22">Lohse A</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany.<br /><searchLink fieldCode="AU" term="%22Fliessbach+K%22">Fliessbach K</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Göttingen Germany.; Department of Psychiatry and Psychotherapy University Medical Center Göttingen University of Göttingen Göttingen Germany.; Department of Medical Sciences Neurosciences and Signaling Group Institute of Biomedicine (iBiMED) University of Aveiro Aveiro Portugal.<br /><searchLink fieldCode="AU" term="%22Hansen+N%22">Hansen N</searchLink>; Department of Psychiatry and Psychotherapy University Medical Center Göttingen University of Göttingen Göttingen Germany.<br /><searchLink fieldCode="AU" term="%22Rostamzadeh+A%22">Rostamzadeh A</searchLink>; Department of Psychiatry Medical Faculty University of Cologne Cologne Germany.<br /><searchLink fieldCode="AU" term="%22Düzel+E%22">Düzel E</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany.; Institute of Cognitive Neurology and Dementia Research (IKND) Otto-von-Guericke University Magdeburg Germany.<br /><searchLink fieldCode="AU" term="%22Glanz+W%22">Glanz W</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany.<br /><searchLink fieldCode="AU" term="%22Incesoy+EI%22">Incesoy EI</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany.; Institute of Cognitive Neurology and Dementia Research (IKND) Otto-von-Guericke University Magdeburg Germany.; Department for Psychiatry and Psychotherapy University Clinic Magdeburg Magdeburg Germany.<br /><searchLink fieldCode="AU" term="%22Butryn+M%22">Butryn M</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Magdeburg Germany.<br /><searchLink fieldCode="AU" term="%22Buerger+K%22">Buerger K</searchLink>; German Center for Neurodegenerative Diseases (DZNE, Munich) Munich Germany.; Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany.<br /><searchLink fieldCode="AU" term="%22Janowitz+D%22">Janowitz D</searchLink>; Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany.<br /><searchLink fieldCode="AU" term="%22Ewers+M%22">Ewers M</searchLink>; German Center for Neurodegenerative Diseases (DZNE, Munich) Munich Germany.; Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany.<br /><searchLink fieldCode="AU" term="%22Perneczky+R%22">Perneczky R</searchLink>; 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Department of Psychosomatic Medicine Rostock University Medical Center Rostock Germany.<br /><searchLink fieldCode="AU" term="%22Goerss+D%22">Goerss D</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Rostock Germany.; Department of Psychosomatic Medicine Rostock University Medical Center Rostock Germany.<br /><searchLink fieldCode="AU" term="%22Laske+C%22">Laske C</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Tübingen Germany.; Section for Dementia Research Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy University of Tübingen Tübingen Germany.<br /><searchLink fieldCode="AU" term="%22Munk+MH%22">Munk MH</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Tübingen Germany.; Department of Psychiatry and Psychotherapy University of Tübingen Tübingen Germany.<br /><searchLink fieldCode="AU" term="%22Sanzenbacher+C%22">Sanzenbacher C</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Tübingen Germany.<br /><searchLink fieldCode="AU" term="%22Spottke+A%22">Spottke A</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurology University of Bonn Bonn Germany.<br /><searchLink fieldCode="AU" term="%22Roy-Kluth+N%22">Roy-Kluth N</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.<br /><searchLink fieldCode="AU" term="%22Heneka+MT%22">Heneka MT</searchLink>; Luxembourg Centre for Systems Biomedicine (LCSB) University of Luxembourg Belvaux Luxemburg.<br /><searchLink fieldCode="AU" term="%22Brosseron+F%22">Brosseron F</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry University of Bonn Medical Center Bonn Germany.<br /><searchLink fieldCode="AU" term="%22Wolfsgruber+S%22">Wolfsgruber S</searchLink>; German Center for Neurodegenerative Diseases (DZNE) Bonn Germany.; 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Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) University of Cologne Köln Germany.<br /><searchLink fieldCode="AU" term="%22Bannach+O%22">Bannach O</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.<br /><searchLink fieldCode="AU" term="%22Willbold+D%22">Willbold D</searchLink>; Institute of Biological Information Processing (Structural Biochemistry: IBI-7) Forschungszentrum Jülich GmbH Jülich Germany.; attyloid GmbH Düsseldorf Germany.; Institut für Physikalische Biologie Heinrich-Heine-Universität Düsseldorf Düsseldorf Germany.<br /><searchLink fieldCode="AU" term="%22Peters+O%22">Peters O</searchLink>; Department of Psychiatry and Psychotherapy Charité Berlin Germany.; German Center for Neurodegenerative Diseases (DZNE) Berlin Germany.
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  Data: <searchLink fieldCode="JN" term="%22101654604%22">Alzheimer's & dementia (Amsterdam, Netherlands)</searchLink> [Alzheimers Dement (Amst)] 2024 Apr 25; Vol. 16 (2), pp. e12589. <i>Date of Electronic Publication: </i>2024 Apr 25 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Alzheimer's+Association%22">Wiley on behalf of the Alzheimer's Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101654604 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2352-8729 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223528729%22">23528729 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement (Amst) <i>Subsets: </i>PubMed not MEDLINE
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      – PersonEntity:
          Name:
            NameFull: Kleineidam L
      – PersonEntity:
          Name:
            NameFull: Stark M
      – PersonEntity:
          Name:
            NameFull: Schmid M
      – PersonEntity:
          Name:
            NameFull: Jessen F
      – PersonEntity:
          Name:
            NameFull: Bannach O
      – PersonEntity:
          Name:
            NameFull: Willbold D
      – PersonEntity:
          Name:
            NameFull: Peters O
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 25
              M: 04
              Text: 2024 Apr 25
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 2352-8729
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Alzheimer's & dementia (Amsterdam, Netherlands)
              Type: main
ResultId 1