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Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19.

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Title: Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19.
Authors: Bramante CT; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Beckman KB; Genomics Center, University of Minnesota, Minneapolis, Minnesota, USA., Mehta T; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Karger AB; Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota, Minneapolis, Minnesota, USA., Odde DJ; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota, USA., Tignanelli CJ; Department of Surgery, Medical School, University of Minnesota, Minneapolis, Minnesota, USA., Buse JB; Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Johnson DM; Genomics Center, University of Minnesota, Minneapolis, Minnesota, USA., Watson RHB; Genomics Center, University of Minnesota, Minneapolis, Minnesota, USA., Daniel JJ; Genomics Center, University of Minnesota, Minneapolis, Minnesota, USA., Liebovitz DM; General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Nicklas JM; General Internal Medicine, University of Colorado, School of Medicine, Aurora, Colorado, USA., Cohen K; UnitedHealth Group, Optum Labs, Minnetonka, Minnesota, USA., Puskarich MA; Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota, USA., Belani HK; Department of Medicine, Olive View-University of California, Los Angeles, California, USA., Siegel LK; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Klatt NR; Department of Surgery, Medical School, University of Minnesota, Minneapolis, Minnesota, USA., Anderson B; Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA.; Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Hartman KM; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Rao V; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Hagen AA; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Patel B; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Fenno SL; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Avula N; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Reddy NV; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Erickson SM; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Fricton RD; General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Lee S; General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Griffiths G; General Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Pullen MF; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Thompson JL; Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Sherwood NE; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Murray TA; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Rose MR; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Boulware DR; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Huling JD; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Corporate Authors: COVID-OUT Study Team
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Aug 16; Vol. 79 (2), pp. 354-363.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
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  Data: Favorable Antiviral Effect of Metformin on SARS-CoV-2 Viral Load in a Randomized, Placebo-Controlled Clinical Trial of COVID-19.
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