Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer (TOPAZ-1): patient-reported outcomes from a randomised, double-blind, placebo-controlled, phase 3 trial.

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Title: Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer (TOPAZ-1): patient-reported outcomes from a randomised, double-blind, placebo-controlled, phase 3 trial.
Authors: Burris HA 3rd; Sarah Cannon Research Institute, Tennessee Oncology, Nashville, TN, USA. Electronic address: howard.burris@sarahcannon.com., Okusaka T; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan., Vogel A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Lee MA; Division of Medical Oncology, Department of Internal Medicine, Seoul St Mary's Hospital, Seoul, South Korea; College of Medicine, Catholic University of Korea, Seoul, South Korea., Takahashi H; Department of Gastroenterological Surgery, Osaka International Cancer Institute, Osaka, Japan., Breder V; Department of Chemotherapy, N N Blokhin Russian Cancer Research Center, Moscow, Russia., Blanc JF; Department of Hepato-gastroenterology and Digestive Oncology, Hôpital Haut-Lévêque, Bordeaux, France., Li J; Department of Oncology, First Affiliated Hospital of Nanchang University, Nanchang, China., Bachini M; Cholangiocarcinoma Foundation, Herriman, UT, USA., Żotkiewicz M; AstraZeneca, Warsaw, Poland., Abraham J; Patient Centered Solutions, New York, NY, USA., Patel N; AstraZeneca, Gaithersburg, MD, USA., Wang J; AstraZeneca, Gaithersburg, MD, USA., Ali M; AstraZeneca, Gaithersburg, MD, USA., Rokutanda N; AstraZeneca, Gaithersburg, MD, USA., Cohen G; AstraZeneca, Gaithersburg, MD, USA., Oh DY; Division of Medical Oncology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
Source: The Lancet. Oncology [Lancet Oncol] 2024 May; Vol. 25 (5), pp. 626-635.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't; Multicenter Study
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Durvalumab plus gemcitabine and cisplatin in advanced biliary tract cancer (TOPAZ-1): patient-reported outcomes from a randomised, double-blind, placebo-controlled, phase 3 trial.
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  Data: <searchLink fieldCode="AU" term="%22Burris+HA+3rd%22">Burris HA 3rd</searchLink>; Sarah Cannon Research Institute, Tennessee Oncology, Nashville, TN, USA. Electronic address: howard.burris@sarahcannon.com.<br /><searchLink fieldCode="AU" term="%22Okusaka+T%22">Okusaka T</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Vogel+A%22">Vogel A</searchLink>; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Lee+MA%22">Lee MA</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Seoul St Mary's Hospital, Seoul, South Korea; College of Medicine, Catholic University of Korea, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Takahashi+H%22">Takahashi H</searchLink>; Department of Gastroenterological Surgery, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Breder+V%22">Breder V</searchLink>; Department of Chemotherapy, N N Blokhin Russian Cancer Research Center, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Blanc+JF%22">Blanc JF</searchLink>; Department of Hepato-gastroenterology and Digestive Oncology, Hôpital Haut-Lévêque, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Oncology, First Affiliated Hospital of Nanchang University, Nanchang, China.<br /><searchLink fieldCode="AU" term="%22Bachini+M%22">Bachini M</searchLink>; Cholangiocarcinoma Foundation, Herriman, UT, USA.<br /><searchLink fieldCode="AU" term="%22Żotkiewicz+M%22">Żotkiewicz M</searchLink>; AstraZeneca, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Abraham+J%22">Abraham J</searchLink>; Patient Centered Solutions, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Patel+N%22">Patel N</searchLink>; AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ali+M%22">Ali M</searchLink>; AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rokutanda+N%22">Rokutanda N</searchLink>; AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+G%22">Cohen G</searchLink>; AstraZeneca, Gaithersburg, MD, USA.<br /><searchLink fieldCode="AU" term="%22Oh+DY%22">Oh DY</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.
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  Data: <searchLink fieldCode="JN" term="%22100957246%22">The Lancet. Oncology</searchLink> [Lancet Oncol] 2024 May; Vol. 25 (5), pp. 626-635.
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  Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lancet+Pub%2E+Group%22">Lancet Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100957246 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-5488 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214702045%22">14702045 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Oncol <i>Subsets: </i>MEDLINE
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              Text: 2024 May
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