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Genetic variation and pesticide exposure influence blood DNA methylation signatures in females with early-stage Parkinson's disease.

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Title: Genetic variation and pesticide exposure influence blood DNA methylation signatures in females with early-stage Parkinson's disease.
Authors: Schaffner SL; Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Casazza W; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Bioinformatics Graduate Program, University of British Columbia, Vancouver, BC, Canada., Artaud F; Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, CESP, 94805, Villejuif, France., Konwar C; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada., Merrill SM; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada., Domenighetti C; Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, CESP, 94805, Villejuif, France., Schulze-Hentrich JM; Department of Genetics/Epigenetics, Faculty NT, Saarland University, 66041, Saarbrücken, Germany., Lesage S; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Paris, France., Brice A; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Paris, France., Corvol JC; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Paris, France.; Sorbonne University, Assistance Publique Hôpitaux de Paris, Paris Brain Insitute - ICM, Inserm, CNRS, Department of Neurology and CIC Neurosciences, Pitié-Salpêtrière Hospital, Paris, France., Mostafavi S; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Bioinformatics Graduate Program, University of British Columbia, Vancouver, BC, Canada.; Paul Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA., Dennis JK; Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Bioinformatics Graduate Program, University of British Columbia, Vancouver, BC, Canada., Elbaz A; Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, CESP, 94805, Villejuif, France., Kobor MS; Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. michael.kobor@ubc.ca.; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada. michael.kobor@ubc.ca.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. michael.kobor@ubc.ca.
Corporate Authors: DIGPD Study Group
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2024 May 07; Vol. 10 (1), pp. 98. Date of Electronic Publication: 2024 May 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Schaffner+SL%22">Schaffner SL</searchLink>; Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Casazza+W%22">Casazza W</searchLink>; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Bioinformatics Graduate Program, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Artaud+F%22">Artaud F</searchLink>; Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, CESP, 94805, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Konwar+C%22">Konwar C</searchLink>; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Merrill+SM%22">Merrill SM</searchLink>; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Domenighetti+C%22">Domenighetti C</searchLink>; Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, CESP, 94805, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Schulze-Hentrich+JM%22">Schulze-Hentrich JM</searchLink>; Department of Genetics/Epigenetics, Faculty NT, Saarland University, 66041, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Lesage+S%22">Lesage S</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Brice+A%22">Brice A</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Corvol+JC%22">Corvol JC</searchLink>; Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, INSERM, CNRS, Assistance Publique Hôpitaux de Paris, Paris, France.; Sorbonne University, Assistance Publique Hôpitaux de Paris, Paris Brain Insitute - ICM, Inserm, CNRS, Department of Neurology and CIC Neurosciences, Pitié-Salpêtrière Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mostafavi+S%22">Mostafavi S</searchLink>; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Bioinformatics Graduate Program, University of British Columbia, Vancouver, BC, Canada.; Paul Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Dennis+JK%22">Dennis JK</searchLink>; Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.; Bioinformatics Graduate Program, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Elbaz+A%22">Elbaz A</searchLink>; Université Paris-Saclay, UVSQ, Inserm, Gustave Roussy, CESP, 94805, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Kobor+MS%22">Kobor MS</searchLink>; Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. michael.kobor@ubc.ca.; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital, Vancouver, BC, Canada. michael.kobor@ubc.ca.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. michael.kobor@ubc.ca.
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